Patents by Inventor Mariko Nakano
Mariko Nakano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240423520Abstract: A funnel for a small-format blood collection device and system according to embodiments described herein. The system may include a funnel having a first conical portion attached to a second cylindrical portion. At the confluence of these two portions is a shoulder having a raised exterior contour to match a contour of a mating small-format container. The mating of the contours of the shoulder and a matching topside of a small-format container provides for greater stability when utilizing the funnel during a blood collection procedure by way of capillary bleeding.Type: ApplicationFiled: June 26, 2023Publication date: December 26, 2024Inventors: Andrew Chastain, Mariko Nakano, Charles Sailey, Adam Blackwell, Peter Flynn
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Patent number: 9695237Abstract: The present invention provides an anti-human FOLR1 antibody against diseases associated with human FOLR1-expressing cells, which specifically recognizes and binds to an amino acid sequence of human FOLR1 or a conformational structure thereof and also has a high effector activity such as antibody-dependent cellular cytotoxicity activity (ADCC activity). The present invention can provide a monoclonal antibody which specifically recognizes and binds to the amino acid sequence of human FOLR1 or the conformational structure thereof and also has ADCC activity and CDC activity, or an antibody fragment thereof, a DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by introducing the vector, a method for producing the antibody or the antibody fragment thereof using the transformant, and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment as an active ingredient.Type: GrantFiled: September 30, 2015Date of Patent: July 4, 2017Assignee: KYOWA HAKKO KIRIN CO., LTDInventors: Munetoshi Ando, Hiroshi Ando, Mariko Nakano, Naoya Kameyama, Tsuguo Kubota
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Publication number: 20160060340Abstract: The present invention provides an anti-human FOLR1 antibody against diseases associated with human FOLR1-expressing cells, which specifically recognizes and binds to an amino acid sequence of human FOLR1 or a conformational structure thereof and also has a high effector activity such as antibody-dependent cellular cytotoxicity activity (ADCC activity). The present invention can provide a monoclonal antibody which specifically recognizes and binds to the amino acid sequence of human FOLR1 or the conformational structure thereof and also has ADCC activity and CDC activity, or an antibody fragment thereof, a DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by introducing the vector, a method for producing the antibody or the antibody fragment thereof using the transformant, and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment as an active ingredient.Type: ApplicationFiled: September 30, 2015Publication date: March 3, 2016Applicant: KYOWA HAKKO KIRIN CO., LTDInventors: Munetoshi ANDO, Hiroshi ANDO, Mariko NAKANO, Naoya KAMEYAMA, Tsuguo KUBOTA
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Patent number: 9207238Abstract: The present invention provides an anti-human FOLR1 antibody against diseases associated with human FOLR1-expressing cells, which specifically recognizes and binds to an amino acid sequence of human FOLR1 or a conformational structure thereof and also has a high effector activity such as antibody-dependent cellular cytotoxicity activity (ADCC activity). The present invention can provide a monoclonal antibody which specifically recognizes and binds to the amino acid sequence of human FOLR1 or the conformational structure thereof and also has ADCC activity and CDC activity, or an antibody fragment thereof, a DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by introducing the vector, a method for producing the antibody or the antibody fragment thereof using the transformant, and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment as an active ingredient.Type: GrantFiled: November 25, 2013Date of Patent: December 8, 2015Assignee: KYOWA HAKKO KIRIN CO., LTD.Inventors: Munetoshi Ando, Hiroshi Ando, Mariko Nakano, Naoya Kameyama, Tsuguo Kubota
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Publication number: 20140205610Abstract: The present invention provides an anti-human FOLR1 antibody against diseases associated with human FOLR1-expressing cells, which specifically recognizes and binds to an amino acid sequence of human FOLR1 or a conformational structure thereof and also has a high effector activity such as antibody-dependent cellular cytotoxicity activity (ADCC activity). The present invention can provide a monoclonal antibody which specifically recognizes and binds to the amino acid sequence of human FOLR1 or the conformational structure thereof and also has ADCC activity and CDC activity, or an antibody fragment thereof, a DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by introducing the vector, a method for producing the antibody or the antibody fragment thereof using the transformant, and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment as an active ingredient.Type: ApplicationFiled: November 25, 2013Publication date: July 24, 2014Applicant: KYOWA HAKKO KIRIN CO., LTDInventors: Munetoshi ANDO, Hiroshi ANDO, Mariko NAKANO, Naoya KAMEYAMA, Tsuguo KUBOTA
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Patent number: 8076458Abstract: An object of the present invention is to provide a monoclonal antibody which is useful as a diagnostic agent or a therapeutic agent for a disease relating to a polypeptide encoded by Claudin-4 (hereinafter referred to as “CLDN4”) gene or a polypeptide encoded by a Claudin-3 (hereinafter referred to as “CLDN3”) gene, or a method for using the same.Type: GrantFiled: March 17, 2008Date of Patent: December 13, 2011Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: So Ohta, Hiroshi Ando, Masayo Suzuki, Shinobu Kawamoto, Mariko Nakano, Kazuyasu Nakamura
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Publication number: 20090202556Abstract: An object of the present invention is to provide a monoclonal antibody which is useful as a diagnostic agent or a therapeutic agent for a disease relating to a polypeptide encoded by Claudin-4 (hereinafter referred to as “CLDN4”) gene or a polypeptide encoded by a Claudin-3 (hereinafter referred to as “CLDN3”) gene, or a method for using the same.Type: ApplicationFiled: March 17, 2008Publication date: August 13, 2009Applicant: KYOWA HAKKO KIRIN CO., LTD.Inventors: So OHTA, Hiroshi ANDO, Masayo SUZUKI, Shinobu KAWAMOTO, Mariko NAKANO, Kazuyasu Nakamura
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Patent number: 4211532Abstract: Test composition and test stick for detection of chloride ion in cow's milk, which composition comprises a protected silver chromate colloidal substance, a surface active agent and a buffer agent having a pH value ranging from 2 to 7, and which test stick comprises a carrier, protected silver chromate colloidal substance, a surface active agent and a buffer agent having a pH value ranging from 2 to 7; and a method for producing the test stick.Type: GrantFiled: July 13, 1978Date of Patent: July 8, 1980Assignee: Toyo Roshi Kaisha Ltd.Inventors: Shizen Tobari, Mariko Nakano