Patents by Inventor Marilyn Armstrong

Marilyn Armstrong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10371706
    Abstract: The present invention relates to a method for determining predisposition of a subject to developing renal dysfunction induced by physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of:—a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject prior to physical trauma, prior to a hypotensive event, prior to sepsis, and/or prior to septic shock syndrome; b. determining if the subject is predisposed to developing renal dysfunction following physical trauma, hypotension, sepsis and/or septic shock syndrome on the basis of the level of an anti-inflammatory cytokine determined in step a).
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: August 6, 2019
    Assignees: THE QUEEN'S UNIVERSITY OF BELFAST, BELFAST HEALTH AND SOCIAL CARE TRUST
    Inventors: William Thomas McBride, Marilyn Armstrong
  • Patent number: 10267807
    Abstract: The present invention relates to a method for diagnosing and/or prognosing renal dysfunction. The method comprises the steps of: —(a) determining the level of an anti-inflammatory cytokine present in a urine sample from a subject prior to physical trauma, prior to a hypotensive event, prior to sepsis, and/or prior to septic shock syndrome; (b) determining the level of the anti-inflammatory cytokine present in a urine sample from the subject following physical trauma, following or during a hypotensive event, following or during sepsis, and/or following or during septic shock syndrome; (c) calculating the difference between the level of the anti-inflammatory cytokine determined in step a) from the level of the anti-inflammatory cytokine determined in step b), and (d) providing a diagnosis and/or prognosis on the basis of a comparison between the difference calculated in step c) and the difference calculated in step c) when steps a) and b) are practiced on a control group.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: April 23, 2019
    Assignees: BELFAST HEALTH AND SOCIAL CARE TRUST, THE QUEEN'S UNIVERSITY OF BELFAST
    Inventors: William Thomas McBride, Marilyn Armstrong
  • Patent number: 10094839
    Abstract: The present invention relates to a method for a method for predicting the development of renal dysfunction in a subject following physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of: —a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject after physical trauma, after a hypotensive event, after sepsis, and/or after septic shock syndrome; b. predicting the development in the subject of renal dysfunction on the basis of the level of an anti-inflammatory cytokine determined in step a).
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 9, 2018
    Assignees: THE QUEEN'S UNIVERSITY OF BELFAST, BELFAST HEALTH AND SOCIAL CARE TRUST
    Inventors: William Thomas McBride, Marilyn Armstrong
  • Publication number: 20150185229
    Abstract: The present invention relates to a method for determining predisposition of a subject to developing renal dysfunction induced by physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of:—a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject prior to physical trauma, prior to a hypotensive event, prior to sepsis, and/or prior to septic shock syndrome; b. determining if the subject is predisposed to developing renal dysfunction following physical trauma, hypotension, sepsis and/or septic shock syndrome on the basis of the level of an anti-inflammatory cytokine determined in step a).
    Type: Application
    Filed: June 13, 2013
    Publication date: July 2, 2015
    Applicants: THE QUEEN'S UNIVERSITY OF BELFAST, BELFAST HEALTH AND SOCIAL CARE TRUST
    Inventors: William Thomas McBride, Marilyn Armstrong
  • Publication number: 20150126480
    Abstract: The present invention relates to a method for a method for predicting the development of renal dysfunction in a subject following physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of: —a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject after physical trauma, after a hypotensive event, after sepsis, and/or after septic shock syndrome; b. predicting the development in the subject of renal dysfunction on the basis of the level of an anti-inflammatory cytokine determined in step a).
    Type: Application
    Filed: June 13, 2013
    Publication date: May 7, 2015
    Applicants: The Queen's University of Belfast, BELFAST HEALTH AND SOCIAL CARE TRUST
    Inventors: William Thomas McBride, Marilyn Armstrong
  • Publication number: 20110071121
    Abstract: The present invention relates to a method for diagnosing and/or prognosing renal dysfunction. The method comprises the steps of:—(a) determining the level of an anti-inflammatory cytokine present in a urine sample from a subject prior to physical trauma, prior to a hypotensive event, prior to sepsis, and/or prior to septic shock syndrome; (b) determining the level of the anti-inflammatory cytokine present in a urine sample from the subject following physical trauma, following or during a hypotensive event, following or during sepsis, and/or following or during septic shock syndrome; (c) calculating the difference between the level of the anti-inflammatory cytokine determined in step a) from the level of the anti-inflammatory cytokine determined in step b), and (d) providing a diagnosis and/or prognosis on the basis of a comparison between the difference calculated in step c) and the difference calculated in step c) when steps a) and b) are practiced on a control group.
    Type: Application
    Filed: April 21, 2009
    Publication date: March 24, 2011
    Inventors: William Thomas McBride, Marilyn Armstrong