Abstract: A sanitary handle cover system for shopping carts that includes a dual layer exterior shield and an interior foam cushion assembly that are each positioned over the existing handle of a shopping card to provide multiple barrier layers between the user and the existing shopping cart handle. The dual layer exterior shield includes a fluid impermeable layer and a fluid absorbent layer. The exterior shield preferably includes an exterior fabric layer such as terry cloth and an fluid impermeable layer such as a flexible plastic film that are stitched together and securable about the interior foam cushion assembly by a pair of securing straps and snaps.