Patents by Inventor Marina A. Madre

Marina A. Madre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS
    Publication number: 20100029646
    Abstract: The present application discloses prodrugs of substituted 3,3-diphenyl-1,3-dihydro-indol-2-one compounds having the general formula (I). The 4-position of the phenyl moieties and the N-position of the indole represent useful handles for the introduction of particular prodrug groups, in particular those comprising an amino acid moiety. The prodrug compounds are believed to be useful for the treatment of cancer in a mammal, possibly in combination with one or more other chemotherapeutic agents.
    Type: Application
    Filed: December 11, 2007
    Publication date: February 4, 2010
    Applicant: Topo Target A/S
    Inventors: Mette Knak Christensen, Fredrik Bjoerkling, Martins Ikaunieks, Andrei Zaichenko, Vija Gailite, Einars Loza, Ivars Kalvinsh, Marina Madre
  • Pyrrolopyridines Useful in the Treatment of Inflammation
    Publication number: 20090048285
    Abstract: There is provided compounds of formula (I), wherein X1, R1, R2, Y1, Y2, Y3 and Y4 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: January 19, 2006
    Publication date: February 19, 2009
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Pavels Arsenjans, Ivars Kalvins, Edgars Suna, Martins Katkevics, Marina Madre, Vita Ozola
  • 9-substituted guanines
    Patent number: 4916225
    Abstract: Novel compounds, 9-substituted guanines, with the following general formula ##STR1## where R' is acetyl;R" is 2-tetrahydrofuryl or 2-tetrahydropyranyl.The proposed compounds have antiviral activity.
    Type: Grant
    Filed: July 14, 1988
    Date of Patent: April 10, 1990
    Assignees: Institut Organicheskogo Sinteza Akademii nauk Latviiskoi SSR, Belorussky Nauchno-Issledovatelsky Institute Epidemiologii i Mikrobiologii
    Inventors: Regina A. Zhuk, Marger J. Lidak, Marina A. Madre, Veniamin I. Votyakov, Olga T. Andreeva, Evgeny I. Boreko, Ljudmila V. Korobchenko, Vyacheslav A. Rusyaev, Olga I. Starkova