Patents by Inventor Marina Dadaian

Marina Dadaian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for manufacturing factor VIII having an improved ratio of FVIII:C/FVIII/AG
    Patent number: 10822393
    Abstract: A process for manufacturing of a Factor VIII product having a ratio of FVIII:C/FVIII:Ag of at least 0.7 in the Factor VIII product by using chromatography wherein at least one chromatographic step is performed by means of employing; An affinity chromatography resin having an affinity for specifically binding of Factor VIII which is effected by an affinity ligand which is immobilised on the affinity chromatography resin, said affinity ligand is a 13 kD yeast derived Fab antibody fragment directed to the Factor VIII molecule. An anionic chromatography resin. A size exclusion resin. A Factor VIII product obtainable according to the process with a monomer content of >98% for treatment of haemophilia and avoiding formation of inhibitors.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: November 3, 2020
    Assignee: OCTAPHARMA AG
    Inventors: Stefan Winge, Marina Dadaian, Erica Johansson, Birte Fuchs
  • A PROCESS FOR MANUFACTURING FACTOR VIII HAVING AN IMPROVED RATIO OF FVIII:C/FVIII:AG
    Publication number: 20160340410
    Abstract: A process for manufacturing of a Factor VIII product having a ratio of FVIII:C/FVIII:Ag of at least 0.7 in the Factor VIII product by using chromatography wherein at least one chromatographic step is performed by means of employing; An affinity chromatography resin having an affinity for specifically binding of Factor VIII which is effected by an affinity ligand which is immobilised on the affinity chromatography resin, said affinity ligand is a 13 kD yeast derived Fab antibody fragment directed to the Factor VIII molecule. An anionic chromatography resin. A size exclusion resin. A Factor VIII product obtainable according to the process with a monomer content of >98% for treatment of haemophilia and avoiding formation of inhibitors.
    Type: Application
    Filed: January 20, 2015
    Publication date: November 24, 2016
    Applicant: OCTAPHARMA AG
    Inventors: Stefan Winge, Marina Dadaian, Erica Johansson, Birte Fuchs