Abstract: Devices and methods of endolumenal formation of gastric sleeves are described. In some embodiments, a bougie capsule section comprises one or more mechanisms to allow flexing that induces a bend through a suction clamping domain that grabs, positions, and holds body lumen tissue (e.g., gastric wall tissue). In some embodiments, a needle drive is configured to allow longitudinal movement of a helical needle through a suturing space defined by the suction clamping domain, optionally while the suction clamping domain is bent. In some embodiments, the suction clamping domain can insert to the stomach in a collapsed configuration, then expanded once in the stomach. Potentially, this allows grabbing and positioning larger and/or deeper folds of tissue for suturing.

Abstract: Suture clips configured to be placed in a predetermined path of a suturing needle that advances through a device inserted to a body cavity, and remotely operated from that position to secure and clamp suturing. In some embodiments, a suture tightening device is placed in the predetermined path and configured to capture the suture and shorten a length of tissue-engaged suture by pulling on the suture. In some embodiments, sensors are placed along the needle path and used to provide an indication of needle position and/or status.

Abstract: Suture clips configured to be placed in a predetermined path of a suturing needle that advances through a device inserted to a body cavity, and remotely operated from that position to secure and clamp suturing. In some embodiments, a suture tightening device is placed in the predetermined path and configured to capture the suture and shorten a length of tissue-engaged suture by pulling on the suture. In some embodiments, sensors are placed along the needle path and used to provide an indication of needle position and/or status.

Abstract: Devices and methods of endolumenal formation of gastric sleeves are described. In some embodiments, a bougie capsule section comprises one or more mechanisms to allow flexing that induces a bend through a suction clamping domain that grabs, positions, and holds body lumen tissue (e.g., gastric wall tissue). In some embodiments, a needle drive is configured to allow longitudinal movement of a helical needle through a suturing space defined by the suction clamping domain, optionally while the suction clamping domain is bent. In some embodiments, the suction clamping domain can insert to the stomach in a collapsed configuration, then expanded once in the stomach. Potentially, this allows grabbing and positioning larger and/or deeper folds of tissue for suturing.