Patents by Inventor Marina Mione

Marina Mione has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of gabaergic cells
    Patent number: 6602680
    Abstract: The invention features methods and compositions for the production of GABAergic cells, particularly GABAergic neurons. Production of GABAergic cells is accomplished by increasing activity of a Dlx gene (e.g., DLX1, DLX2, or DLX5) in an immature neuronal cell. The increase in Dlx activity causes differentiation of the immature neuronal cell into a neuronal cell exhibiting the GABAergic phenotype. The invention also encompasses use of GABAergic cells produced by the method of the invention in, for example, identification of agents that affect GABAergic cell activity and survival, and in replacement therapy.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: August 5, 2003
    Assignee: The Regents of the University of California
    Inventors: John L. Rubenstein, Marina Mione, Stewart Anderson, Thorsten Stuehmer, Kyuson Yun
  • Production of gabaergic cells
    Publication number: 20020151066
    Abstract: The invention features methods and compositions for the production of GABAergic cells, particularly GABAergic neurons. Production of GABAergic cells is accomplished by increasing activity of a Dlx gene (e.g., DLX1, DLX2, or DLX5) in an immature neuronal cell. The increase in Dlx activity causes differentiation of the immature neuronal cell into a neuronal cell exhibiting the GABAergic phenotype. The invention also encompasses use of GABAergic cells produced by the method of the invention in, for example, identification of agents that affect GABAergic cell activity and survival, and in replacement therapy.
    Type: Application
    Filed: July 5, 2001
    Publication date: October 17, 2002
    Inventors: John L. Rubenstein, Marina Mione, Stewart Anderson, Thorsten Stuehmer, Kyuson Yun