Patents by Inventor Marina Shamis

Marina Shamis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED DRUG-CARRYING BACTERIOPHAGES
    Publication number: 20110286971
    Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
    Type: Application
    Filed: June 13, 2011
    Publication date: November 24, 2011
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Iftach YACOBY, Eliora Z. Ron, Doron Shabat, Marina Shamis, Itai Benhar
  • Targeted drug-carrying bacteriophages
    Patent number: 7985573
    Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: July 26, 2011
    Assignee: Ramot At Tel-Aviv University Ltd.
    Inventors: Iftach Yacoby, Eliora Z. Ron, Doron Shabat, Marina Shamis, Itai Benhar
  • TARGETED DRUG-CARRYING BACTERIOPHAGES
    Publication number: 20080057038
    Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
    Type: Application
    Filed: September 6, 2007
    Publication date: March 6, 2008
    Inventors: Iftach Yacoby, Eliora Ron, Doron Shabat, Marina Shamis, Itai Benhar
  • Self-immolative dendrimers releasing many active moieties upon a single activating event
    Publication number: 20050271615
    Abstract: A self-immolative dendrimer capable of releasing all of its tail units upon a single cleavage event, methods of synthesizing same and uses thereof are disclosed.
    Type: Application
    Filed: August 28, 2003
    Publication date: December 8, 2005
    Inventors: Doron Shabat, Benjamin List, Roey Amir, Marina Shamis, Neta Pessah