Patents by Inventor Marina WILLIBALD

Marina WILLIBALD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified cyclopentapeptides and uses thereof
    Patent number: 10919938
    Abstract: The present invention, among others, relates to a compound having a structure according to formula (I) or a pharmaceutically acceptable salt thereof, wherein Xaa1 are the iodo-substituted or methyl-substituted amino acids D- and L-Tyr, iodo-substituted or methyl- substituted D- and L-homotyrosine, iodo-substituted or methyl-substituted D- and L-Phe, iodo-substituted or methyl-substituted D- and L-p-OH-phenylglycine, and iodo-substituted or methyl-substituted D- or L-Trp, Xaa2 to Xaa4 are independently of each other, an optionally N-alkylated natural or unnatural amino acid, R is H or methyl, L is a linker moiety, Ar is a spacer comprising an aromatic moiety, and D comprises, preferably is i) a combination of an organic complexation agent and a radioactive or a detectable label; or ii) a radioactive or a detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins an
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: February 16, 2021
    Assignee: TECHNISCHE UNIVERSITÄT MÜNCHEN
    Inventors: Hans-Jürgen Wester, Margret Schottelius, Theresa Osl, Andreas Poschenrieder, Marina Willibald
  • MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF
    Publication number: 20180037608
    Abstract: The present invention, among others, relates to a compound having a structure according to formula (I) or a pharmaceutically acceptable salt thereof, wherein Xaa1 are the iodo-substituted or methyl-substituted amino acids D- and L-Tyr, iodo-substituted or methyl- substituted D- and L-homotyrosine, iodo-substituted or methyl-substituted D- and L-Phe, iodo-substituted or methyl-substituted D- and L-p-OH-phenylglycine, and iodo-substituted or methyl-substituted D- or L-Trp, Xaa2 to Xaa4 are independently of each other, an optionally N-alkylated natural or unnatural amino acid, R is H or methyl, L is a linker moiety, Ar is a spacer comprising an aromatic moiety, and D comprises, preferably is i) a combination of an organic complexation agent and a radioactive or a detectable label; or ii) a radioactive or a detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins an
    Type: Application
    Filed: June 6, 2014
    Publication date: February 8, 2018
    Applicant: TECHNISCHE UNIVERSITÄT MÜNCHEN
    Inventors: Hans-Jürgen WESTER, Margret SCHOTTELIUS, Theresa OSL, Andreas POSCHENRIEDER, Marina WILLIBALD