Patents by Inventor Marina Yu Etinger

Marina Yu Etinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Candesartan cilexetil polymorphs
    Publication number: 20100121072
    Abstract: Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable excipient with at least one candesartan cilexetil form of the invention.
    Type: Application
    Filed: January 13, 2010
    Publication date: May 13, 2010
    Inventors: Marina Yu Etinger, Boris Fedotev, Tamas Koltai, Ziv Kurgan, Omer Malachi
  • Candesartan cilexetil polymorphs
    Patent number: 7692023
    Abstract: Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable execipient with at least one candesartan cilexetil form of the invention.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: April 6, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marina Yu Etinger, Boris Fedotev, Tamas Koltai, Ziv Kurgan, Omer Malachi
  • Recycling process for preparing sertraline
    Patent number: 7262327
    Abstract: Provided is a recycling process for preparing sertraline, which may be carried out on an industrial scale.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: August 28, 2007
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marioara Mendelovici, Ben-Zion Dolitzky, Marina Yu Etinger, Gennady A. Nisnevich
  • Preparation of candesartan cilexetil
    Patent number: 7098342
    Abstract: The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: August 29, 2006
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marina Yu Etinger, Boris Fedotev, Ben-Zion Dolitzky
  • Crystalline forms of valacyclovir hydrochloride
    Patent number: 6849736
    Abstract: Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: February 1, 2005
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Shlomit Wizel, Judith Aronhime, Valerie Niddam-Hildesheim, Ben-Zion Dolitzky, Marina Yu Etinger, Michael Yuzefovich, Gennady A. Nisnevich, Boris Pertsikov, Boris Tishin, Dina Blasberger
  • Synthesis and purification of valacyclovir
    Patent number: 6849737
    Abstract: The present invention relates to protected valacyclovir, N-tert-butoxycarbonyl-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy] ethyl ester, and a method of making it. The present invention further relates to a method of making valacyclovir including the steps of coupling an amine protected valine selected from N-t-butoxycarbonyl valine and N-formyl valine with acyclovir using a coupling agent to form a protected valacyclovir, and deprotecting the protected valacyclovir to form valacyclovir or a pharmaceutically acceptable salt thereof. The present invention further relates to valacyclovir in pure form, a method of making pure valacyclovir, and to compositions containing pure valacyclovir.
    Type: Grant
    Filed: November 13, 2002
    Date of Patent: February 1, 2005
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marina Yu Etinger, Lev M. Yudovich, Michael Yuzefovich, Gennady A. Nisnevich, Ben Zion Dolitzky, Boris Pertsikov, Boris Tishin, Dina Blasberger
  • Synthesis and purification of valacyclovir
    Publication number: 20030153757
    Abstract: The present invention relates to protected valacyclovir, N-tert-butoxycarbonyl-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy] ethyl ester, and a method of making it. The present invention further relates to a method of making valacyclovir including the steps of coupling an amine protected valine selected from N-t-butoxycarbonyl valine and N-formyl valine with acyclovir using a coupling agent to form a protected valacyclovir, and deprotecting the protected valacyclovir to form valacyclovir or a pharmaceutically acceptable salt thereof. The present invention further relates to valacyclovir in pure form, a method of making pure valacyclovir, and to compositions containing pure valacyclovir.
    Type: Application
    Filed: November 13, 2002
    Publication date: August 14, 2003
    Inventors: Marina Yu Etinger, Lev M. Yudovich, Michael Yuzefovich, Gennady A. Nisnevich, Ben Zion Dolitzky, Boris Pertsikov, Boris Tishin, Dina Blasberger
  • Crystalline forms of valacyclovir hydrochloride
    Publication number: 20030114470
    Abstract: Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate.
    Type: Application
    Filed: September 6, 2002
    Publication date: June 19, 2003
    Inventors: Shlomit Wizel, Judith Aronhime, Valerie Niddam-Hildesheim, Ben-Zion Dolitzky, Marina Yu Etinger, Michael Yuzefovich, Gennady A. Nisnevich, Boris Pertsikov, Boris Tishin, Dina Blasberger