Patents by Inventor Marino Nebuloni

Marino Nebuloni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
    Patent number: 9636408
    Abstract: The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 2, 2017
    Assignee: TONIX PHARMA HOLDINGS LIMITED
    Inventors: Marino Nebuloni, Patrizia Colombo
  • EUTECTIC ISOMETHEPTENE MUCATE
    Publication number: 20150258197
    Abstract: The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of racemic isometheptene mucate and mannitol or (R)-isometheptene mucate and mannitol.
    Type: Application
    Filed: March 13, 2015
    Publication date: September 17, 2015
    Inventors: Seth Lederman, Marino Nebuloni, Patrizia Colombo
  • EUTECTIC FORMULATIONS OF CYCLOBENZAPRINE HYDROCHLORIDE AND AMITRIPTYLINE HYDROCHLORIDE
    Publication number: 20140336264
    Abstract: The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
    Type: Application
    Filed: March 14, 2014
    Publication date: November 13, 2014
    Applicant: TONIX PHARMACEUTICALS, INC.
    Inventors: Marino Nebuloni, Patrizia Colombo
  • Complex of amorphous tomoxiprole and cyclodextrin with fast dissolution rate and process for the preparation thereof
    Patent number: 8791269
    Abstract: A stable complex of tomoxiprole with 2-hydroxypropyl-beta-cyclodextrin with fast dissolution rate and rapid absorption wherein amorphous tomoxiprole forms a complex with 2-hydroxypropyl-beta-cyclodextrin in about equimolecular ratio. The complex shows a remarkably faster dissolution rate and absorption with respect to crystalline tomoxiprole and is particularly suitable for the production of pharmaceutical oral dosage forms, such as tablets and capsules, where rapid onset of therapeutical action is required. A method of manufacture of the complex is also described and claimed.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: July 29, 2014
    Assignees: Fondazione Istituto Insubrico di Ricerca per la Vita, Fondazione Cariplo
    Inventors: Alberto Milanese, Marino Nebuloni, Lucia Carrano
  • COMPLEX OF AMORPHOUS TOMOXIPROLE AND CYCLODEXTRIN WITH FAST DISSOLUTION RATE AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20140128343
    Abstract: A stable complex of tomoxiprole with 2-hydroxypropyl-beta-cyclodextrin with fast dissolution rate and rapid absorption wherein amorphous tomoxiprole forms a complex with 2-hydroxypropyl-beta-cyclodextrin in about equimolecular ratio. The complex shows a remarkably faster dissolution rate and absorption with respect to crystalline tomoxiprole and is particularly suitable for the production of pharmaceutical oral dosage forms, such as tablets and capsules, where rapid onset of therapeutical action is required. A method of manufacture of the complex is also described and claimed.
    Type: Application
    Filed: June 14, 2012
    Publication date: May 8, 2014
    Applicants: FONDAZIONE CARIPLO, FONDAZIONE ISTITUTO INSUBRICO DI RICERCA PER LA VITA
    Inventors: Alberto Milanese, Marino Nebuloni, Lucia Carrano
  • Rifapentine hydrohalides
    Patent number: 5306715
    Abstract: A solid rifapentine hydrohalide useful for anti-bacterial purposes.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: April 26, 1994
    Assignee: Gruppo Lepetit SpA
    Inventors: Emilio Occelli, Marino Nebuloni, Bruno Cavalleri