Patents by Inventor Marino Nebuloni

Marino Nebuloni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complex of amorphous tomoxiprole and cyclodextrin with fast dissolution rate and process for the preparation thereof
    Patent number: 8791269
    Abstract: A stable complex of tomoxiprole with 2-hydroxypropyl-beta-cyclodextrin with fast dissolution rate and rapid absorption wherein amorphous tomoxiprole forms a complex with 2-hydroxypropyl-beta-cyclodextrin in about equimolecular ratio. The complex shows a remarkably faster dissolution rate and absorption with respect to crystalline tomoxiprole and is particularly suitable for the production of pharmaceutical oral dosage forms, such as tablets and capsules, where rapid onset of therapeutical action is required. A method of manufacture of the complex is also described and claimed.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: July 29, 2014
    Assignees: Fondazione Istituto Insubrico di Ricerca per la Vita, Fondazione Cariplo
    Inventors: Alberto Milanese, Marino Nebuloni, Lucia Carrano
  • COMPLEX OF AMORPHOUS TOMOXIPROLE AND CYCLODEXTRIN WITH FAST DISSOLUTION RATE AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20140128343
    Abstract: A stable complex of tomoxiprole with 2-hydroxypropyl-beta-cyclodextrin with fast dissolution rate and rapid absorption wherein amorphous tomoxiprole forms a complex with 2-hydroxypropyl-beta-cyclodextrin in about equimolecular ratio. The complex shows a remarkably faster dissolution rate and absorption with respect to crystalline tomoxiprole and is particularly suitable for the production of pharmaceutical oral dosage forms, such as tablets and capsules, where rapid onset of therapeutical action is required. A method of manufacture of the complex is also described and claimed.
    Type: Application
    Filed: June 14, 2012
    Publication date: May 8, 2014
    Applicants: FONDAZIONE CARIPLO, FONDAZIONE ISTITUTO INSUBRICO DI RICERCA PER LA VITA
    Inventors: Alberto Milanese, Marino Nebuloni, Lucia Carrano
  • Rifapentine hydrohalides
    Patent number: 5306715
    Abstract: A solid rifapentine hydrohalide useful for anti-bacterial purposes.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: April 26, 1994
    Assignee: Gruppo Lepetit SpA
    Inventors: Emilio Occelli, Marino Nebuloni, Bruno Cavalleri