Patents by Inventor Marinus A. De Ruiter

Marinus A. De Ruiter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized gonadotropin containing preparations
    Patent number: 5384132
    Abstract: Disclosed are lyophilized gonadotropin containing preparations containing a dicarboxylic acid salt stabilizer. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with, and at least partially capable of stabilization by, the particular stabilizer in lyophilized form. The preparations contain a sufficient amount of dicarboxylic acid salt to stabilize the protein in freeze-dried form for a desired time at a desired temperature. Typical dicarboxylic acid salts disclosed are the salts of citric, tartaric, and aspartic acids. The preparations preferably include a non-reducing disaccharide to increase the collapse temperature of the solution to be lyophilized. Methods of making the preparations in lyophilized form and the resulting injectable preparations are also disclosed.
    Type: Grant
    Filed: September 3, 1993
    Date of Patent: January 24, 1995
    Assignee: Akzo N.V.
    Inventors: Andreas L. J. De Meere, Marinus A. De Ruiter
  • Stabilized gonadotropin containing preparations
    Patent number: 5270057
    Abstract: Disclosed are lyophilized gonadotropin containing preparations containing a dicarboxylic acid salt stabilizer. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with, and at least partially capable of stabilization by, the particular stabilizer in lyophilized form. The preparations contain a sufficient amount of dicarboxylic acid salt to stabilize the protein in freeze-dried form for a desired time at a desired temperature. Typical dicarboxylic acid salts disclosed are the salts of citric, tartaric, and aspartic acids. The preparations preferably include a non-reducing disaccharide to increase the collapse temperature of the solution to be lyophilized. Methods of making the preparations in lyophilized form and the resulting injectable preparations are also disclosed.
    Type: Grant
    Filed: July 13, 1992
    Date of Patent: December 14, 1993
    Assignee: Akzo N.V.
    Inventors: Andreas L. J. de Meere, Marinus A. De Ruiter
  • plant named ‘HR 01’
    Patent number: PP24048
    Abstract: A new cultivar of Paeonia plant named ‘HR 01’, characterized by its large fully double flowers that are pure white in color and highly fragrant.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: November 26, 2013
    Assignee: De Wilgenhoek Beheer B.V.
    Inventor: Hendrik Marinus de Ruiter