Patents by Inventor Mario Andres PIZZORNO

Mario Andres PIZZORNO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION COMPRISING DILTIAZEM FOR TREATING A VIRAL INFECTION CAUSED BY SARS-COV-2 VIRUSES
    Publication number: 20230210866
    Abstract: The present invention relates to a pharmaceutical composition comprising Diltiazem in a suitable pharmaceutical carrier for its therapeutic use in the prevention and/or treatment of a viral infection caused by the SARS-CoV-2 virus, referred to as COVID-19 disease.
    Type: Application
    Filed: March 10, 2021
    Publication date: July 6, 2023
    Inventors: Manuel ROSA-CALATRAVA, Olivier TERRIER, Mario Andres PIZZORNO, Aurelien TRAVERSIER, Blandine PADEY, Thomas JULIEN
  • COMBINATION OF DILTIAZEM AND VIRAL POLYMERASE INHIBITORS
    Publication number: 20230075092
    Abstract: The invention relates to a combination of Diltiazem and at least one viral polymerase inhibitor compound selected from among Baloxavir marboxil, Pimodivir, RO-7 and CC-42344. The invention relates in particular to the therapeutic use of said combination in the prevention and/or treatment of a viral infection, in particular of the respiratory and/or intestinal tract of a human or animal body.
    Type: Application
    Filed: January 12, 2021
    Publication date: March 9, 2023
    Inventors: Olivier TERRIER, Manuel ROSA-CALATRAVA, Guy BOIVIN, Mario-Andres PIZZORNO, Blandine PADEY
  • Attenuated virus strain and use thereof as a vaccine
    Patent number: 11504424
    Abstract: The present invention relates to an attenuated virus strain derived from a human metapneumovirus strain comprising the genome sequence represented by sequence SEQ ID NO. 1, said attenuated strain comprising one or more genetic modifications of said sequence SEQ ID NO. 1 attenuating the virulence of said strain.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: November 22, 2022
    Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE DE LYON, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE LAVAL
    Inventors: Manuel Rosa-Calatrava, Guy Boivin, Julia Dubois, Mario Andres Pizzorno, Olivier Terrier, Marie-Eve Hamelin, Marie-Helene Cavanagh
  • PRODUCTION OF VIRAL VACCINES ON AN AVIAN CELL LINE
    Publication number: 20220054618
    Abstract: The present invention relates to the use of the immortalised cell line ECACC 09070703, deposited on 7 Jul. 2009 at the European Collection of Authenticated Cell Cultures (ECACC, Salisbury, UK) under the number 09070703, for the production of a viral vaccine constituted of an attenuated strain derived from a human metapneumovirus.
    Type: Application
    Filed: December 12, 2019
    Publication date: February 24, 2022
    Inventors: Manuel ROSA-CALATRAVA, Guy BOIVIN, Julia DUBOIS, Mario Andres PIZZORNO, Olivier TERRIER, Aurélien TRAVERSIER
  • NEW ATTENUATED VIRUS STRAIN AND USE THEREOF AS A VACCINE
    Publication number: 20210283239
    Abstract: The present invention relates to an attenuated virus strain derived from a human metapneumovirus strain comprising the genome sequence represented by sequence SEQ ID NO. 1, said attenuated strain comprising one or more genetic modifications of said sequence SEQ ID NO. 1 attenuating the virulence of said strain.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 16, 2021
    Inventors: Manuel ROSA-CALATRAVA, Guy BOIVIN, Julia DUBOIS, Mario Andres PIZZORNO, Olivier TERRIER, Marie-Eve HAMELIN, Marie-Helene CAVANAGH
  • DILTIAZEM FOR USE IN THE TREATMENT OF MICROBIAL INFECTIONS
    Publication number: 20210154205
    Abstract: The present invention relates to diltiazem for use as an agent for activating the expression of at least one gene encoding a type III interferon, in the prevention and/or treatment of infections by at least one pathogenic microorganism of the epithelia of the respiratory and/or intestinal tracts.
    Type: Application
    Filed: May 23, 2019
    Publication date: May 27, 2021
    Inventors: Manuel ROSA-CALATRAVA, Olivier TERRIER, Claire NICOLAS DE LAMBALLERIE, Guy BOIVIN, Mario Andres PIZZORNO