Patents by Inventor Mario Becker

Mario Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11845921
    Abstract: The invention relates to a device for examining a medium (100) inside a bioreactor (200; 201), comprising a sample-taking module (20) for taking a sample of the medium (100). The sample-taking module (20) comprises an uptake region (10; 10a; 10b) that can be arranged to make contact with the medium (100) inside the bioreactor (200; 201). At least two different membranes (15, 16) are positioned on the uptake region (10; 10a; 10b) of said sample-taking module (20), for the purpose of taking a sample of the medium (100).
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: December 19, 2023
    Inventors: Christian Grimm, Henry Weichert, Mario Becker
  • Patent number: 10968421
    Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: April 6, 2021
    Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
  • Patent number: 10955812
    Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: March 23, 2021
    Inventors: Stefan Schlack, Lars Boettcher, Mario Becker
  • Patent number: 10802033
    Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: October 13, 2020
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
  • Publication number: 20200291344
    Abstract: The invention relates to a device for examining a medium (100) inside a bioreactor (200; 201), comprising a sample-taking module (20) for taking a sample of the medium (100). The sample-taking module (20) comprises an uptake region (10; 10a; 10b) that can be arranged to make contact with the medium (100) inside the bioreactor (200; 201). At least two different membranes (15, 16) are positioned on the uptake region (10; 10a; 10b) of said sample-taking module (20), for the purpose of taking a sample of the medium (100).
    Type: Application
    Filed: October 18, 2018
    Publication date: September 17, 2020
    Inventors: Christian Grimm, Henry Weichert, Mario Becker
  • Publication number: 20190352595
    Abstract: A method for providing a large amount of cell culture medium (10), in particular for cultivating animal cells, for a large reactor system (12) by using single-use components, comprises the following sequence of steps: a) preparing a concentrated media stock solution (32), b) filling the concentrated media stock solution (32) into single-use containers (40), c) transporting the single-use containers (40) filled with media stock solution (32) to the large reactor system (12), d) aseptically connecting the single-use containers (40) to the large reactor system (12) by means of a single-use hose system (26), e) processing the media stock solution (32) by supplying ultrapure water (24) and/or additives (44), and f) supplying the processed media stock solution (32) into the large reactor system (12).
    Type: Application
    Filed: December 4, 2017
    Publication date: November 21, 2019
    Inventors: Christian GRIMM, Mario BECKER, Christian MANZKE
  • Publication number: 20190219992
    Abstract: A computer system and computer-implemented method are described for controlling and monitoring a process to produce a chemical, pharmaceutical or biotechnological product. The method includes providing a database that stores sets of process parameters to control and monitor a plurality of processes performed in order to produce products, receiving a set of characterizing process parameters that characterize the process, identifying a first set process parameters from the stored sets of process parameters, and controlling and monitoring the process using a successful trajectory that includes a time-based profile of measurements.
    Type: Application
    Filed: May 11, 2017
    Publication date: July 18, 2019
    Applicant: Sartorius Stedim Biotech GmbH
    Inventors: Christian Grimm, Mario Becker, Lars Böttcher, Thorsten Adams
  • Publication number: 20190146452
    Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: Stefan Schlack, Lars Boettcher, Mario Becker
  • Patent number: 10222778
    Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: March 5, 2019
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Stefan Schlack, Lars Boettcher, Mario Becker
  • Publication number: 20190002810
    Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.
    Type: Application
    Filed: April 27, 2016
    Publication date: January 3, 2019
    Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
  • Publication number: 20180188274
    Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).
    Type: Application
    Filed: April 27, 2016
    Publication date: July 5, 2018
    Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
  • Publication number: 20160085230
    Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.
    Type: Application
    Filed: June 24, 2014
    Publication date: March 24, 2016
    Inventors: Stefan Schlack, Lars Boettcher, Mario Becker