Patents by Inventor Mario Becker
Mario Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11845921Abstract: The invention relates to a device for examining a medium (100) inside a bioreactor (200; 201), comprising a sample-taking module (20) for taking a sample of the medium (100). The sample-taking module (20) comprises an uptake region (10; 10a; 10b) that can be arranged to make contact with the medium (100) inside the bioreactor (200; 201). At least two different membranes (15, 16) are positioned on the uptake region (10; 10a; 10b) of said sample-taking module (20), for the purpose of taking a sample of the medium (100).Type: GrantFiled: October 18, 2018Date of Patent: December 19, 2023Inventors: Christian Grimm, Henry Weichert, Mario Becker
-
Patent number: 10968421Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.Type: GrantFiled: April 27, 2016Date of Patent: April 6, 2021Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
-
Patent number: 10955812Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.Type: GrantFiled: January 10, 2019Date of Patent: March 23, 2021Inventors: Stefan Schlack, Lars Boettcher, Mario Becker
-
Patent number: 10802033Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).Type: GrantFiled: April 27, 2016Date of Patent: October 13, 2020Assignee: Sartorius Stedim Biotech GmbHInventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
-
Publication number: 20200291344Abstract: The invention relates to a device for examining a medium (100) inside a bioreactor (200; 201), comprising a sample-taking module (20) for taking a sample of the medium (100). The sample-taking module (20) comprises an uptake region (10; 10a; 10b) that can be arranged to make contact with the medium (100) inside the bioreactor (200; 201). At least two different membranes (15, 16) are positioned on the uptake region (10; 10a; 10b) of said sample-taking module (20), for the purpose of taking a sample of the medium (100).Type: ApplicationFiled: October 18, 2018Publication date: September 17, 2020Inventors: Christian Grimm, Henry Weichert, Mario Becker
-
Publication number: 20190352595Abstract: A method for providing a large amount of cell culture medium (10), in particular for cultivating animal cells, for a large reactor system (12) by using single-use components, comprises the following sequence of steps: a) preparing a concentrated media stock solution (32), b) filling the concentrated media stock solution (32) into single-use containers (40), c) transporting the single-use containers (40) filled with media stock solution (32) to the large reactor system (12), d) aseptically connecting the single-use containers (40) to the large reactor system (12) by means of a single-use hose system (26), e) processing the media stock solution (32) by supplying ultrapure water (24) and/or additives (44), and f) supplying the processed media stock solution (32) into the large reactor system (12).Type: ApplicationFiled: December 4, 2017Publication date: November 21, 2019Inventors: Christian GRIMM, Mario BECKER, Christian MANZKE
-
Publication number: 20190219992Abstract: A computer system and computer-implemented method are described for controlling and monitoring a process to produce a chemical, pharmaceutical or biotechnological product. The method includes providing a database that stores sets of process parameters to control and monitor a plurality of processes performed in order to produce products, receiving a set of characterizing process parameters that characterize the process, identifying a first set process parameters from the stored sets of process parameters, and controlling and monitoring the process using a successful trajectory that includes a time-based profile of measurements.Type: ApplicationFiled: May 11, 2017Publication date: July 18, 2019Applicant: Sartorius Stedim Biotech GmbHInventors: Christian Grimm, Mario Becker, Lars Böttcher, Thorsten Adams
-
Publication number: 20190146452Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.Type: ApplicationFiled: January 10, 2019Publication date: May 16, 2019Inventors: Stefan Schlack, Lars Boettcher, Mario Becker
-
Patent number: 10222778Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.Type: GrantFiled: June 24, 2014Date of Patent: March 5, 2019Assignee: Sartorius Stedim Biotech GmbHInventors: Stefan Schlack, Lars Boettcher, Mario Becker
-
Publication number: 20190002810Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.Type: ApplicationFiled: April 27, 2016Publication date: January 3, 2019Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
-
Publication number: 20180188274Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).Type: ApplicationFiled: April 27, 2016Publication date: July 5, 2018Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
-
Publication number: 20160085230Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.Type: ApplicationFiled: June 24, 2014Publication date: March 24, 2016Inventors: Stefan Schlack, Lars Boettcher, Mario Becker