Patents by Inventor Mario Cazzola

Mario Cazzola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10471063
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: November 12, 2019
    Assignee: Verona Pharma PLC
    Inventors: Michael J. A. Walker, Mario Cazzola, Luigino Calzetta
  • Publication number: 20170266190
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 21, 2017
    Inventors: Michael J.A. Walker, Mario Cazzola, Luigino Calzetta
  • Patent number: 9717732
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a ?2-adrenergic receptor agonist.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 1, 2017
    Assignee: VERONA PHARMA PLC
    Inventors: Michael J. A. Walker, Mario Cazzola, Luigino Calzetta
  • Patent number: 9700558
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: July 11, 2017
    Assignee: VERONA PHARMA PLC
    Inventors: Michael J. A. Walker, Mario Cazzola, Luigino Calzetta
  • Publication number: 20160008363
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a ?2-adrenergic receptor agonist.
    Type: Application
    Filed: March 17, 2014
    Publication date: January 14, 2016
    Applicant: VERONA PHARMA PLC
    Inventors: Michael J.A. Walker, Mario Cazzola, Luigino Calzetta
  • Publication number: 20160000790
    Abstract: The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
    Type: Application
    Filed: March 17, 2014
    Publication date: January 7, 2016
    Applicant: VERONA PHARMA PLC
    Inventors: Michael J.A. Walker, Mario Cazzola, Luigino Calzetta