Patents by Inventor Mario Cindric

Mario Cindric has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detection of amino acid sequence and/or identification of peptides and proteins, by use of a new derivatization reagent and synthesis of 5-formyl-benzene-1,3-disulphonic acid as derivatization reagent
    Patent number: 9581601
    Abstract: Present invention refers to a novel and improved method of derivatization and detection of amino acid sequence and/or identification of proteins, peptides by a new derivatization compound. Precisely, the method discloses a novel approach to derivatization of peptides or proteins by compounds comprising two or more sulfonyl groups and analysis of derivatized analytes in negative mode of operation of mass spectrometer. This method allows unambiguous analysis of amino acid sequence of long-chain peptides/proteins. Also, the invention discloses a novel synthesis procedure of 5-formyl-benzene-1,3-disulphonic acid as derivatization compound.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: February 28, 2017
    Assignee: Rudjer Boskovic Institute
    Inventors: Mario Cindric, Zdenko Hamersak, Ivana Dodig
  • METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT
    Publication number: 20150233937
    Abstract: Present invention refers to a novel and improved method of derivatization and detection of amino acid sequence and/or identification of proteins, peptides by a new derivatization compound. Precisely, the method discloses a novel approach to derivatization of peptides or proteins by compounds comprising two or more sulfonyl groups and analysis of derivatized analytes in negative mode of operation of mass spectrometer. This method allows unambiguous analysis of amino acid sequence of long-chain peptides/proteins. Also, the invention discloses a novel synthesis procedure of 5-formyl-benzene-1,3-disulphonic acid as derivatization compound.
    Type: Application
    Filed: May 18, 2011
    Publication date: August 20, 2015
    Inventors: Mario Cindric, Zdenko Hamersak, Ivana Dodig
  • Mass spectrometry-based protein identification method with selective N-terminus derivatization
    Patent number: 8647880
    Abstract: A method of detection of amino acid sequences and/or identification of proteins and peptides is based on derivatization of peptides or proteins using compounds comprising two or more sulfonyl groups, and subsequent analysis of the derivatized analytes using a mass spectrometer in its negative mode of operation.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: February 11, 2014
    Assignee: Rudjer Bosckovic Institute
    Inventors: Mario Cindric, Sandra Kraljevic Pavelic, Anita Horvatic, Ivana Dodig
  • Mass Spectrometry-Based Protein Identification Method
    Publication number: 20110212531
    Abstract: A method of detection of amino acid sequences and/or identification of proteins and peptides is based on derivatization of peptides or proteins using compounds comprising two or more sulfonyl groups, and subsequent analysis of the derivatized analytes using a mass spectrometer in its negative mode of operation.
    Type: Application
    Filed: April 25, 2011
    Publication date: September 1, 2011
    Inventors: Mario Cindric, Sandra Kraljevic Pavelic, Anita Horvatic, Ivana Dodig