Patents by Inventor Mario F. Tecce

Mario F. Tecce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chlamydia trachomatis serotype D genes
    Patent number: 6248563
    Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E. coli further described.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 19, 2001
    Assignee: Scalvo SpA
    Inventors: Giulio Ratti, Maurizio Comanducci, Mario F. Tecce, Marzia M. Giuliani
  • Recombinant Chlamydia trachomatis pgp3 fusion protein
    Patent number: 6110705
    Abstract: A plasmid isolated from Chlamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections. In particular, the recombinant fusion protein MS2-pgp3D is described, which comprises polypeptide sequences encoded by pCT and is immunogenic in the course of infections in man. A method for preparing the recombinant fusion protein MS2-pgp3D in E. coli is also described.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: August 29, 2000
    Assignee: Chiron S.p.A.
    Inventors: Givlio Ratti, Maurizio Comanducci, Mario F. Tecce, Marzia M. Giuliani
  • Chlamydia trachomatis serotype D proteins
    Patent number: 6096519
    Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E. coli further described.
    Type: Grant
    Filed: November 13, 1997
    Date of Patent: August 1, 2000
    Assignee: Sclavo SpA
    Inventors: Givlio Ratti, Maurizio Comanducci, Mario F. Tecce, Marzia M. Giuliani
  • DNA encoding a synthetic peptide endowed with immunological activity and capable of inducing the production of antibodies with a high specificity towards alpha-fetoprotein
    Patent number: 5206164
    Abstract: A synthetic peptide endowed with immunological activity is disclosed, which is capable of inducing in mammals the formation of anti-peptide antibodies capable of recognizing human alpha-fetoprotein and of reacting with it, and incapable of recognizing albumin or its degradation products, with said peptide being essentially constituted by the aminoacidic sequence of formula (I), corresponding to 38-119 region of human alpha-fetoprotein.Furthermore, the methods and means for preparing said peptide by means of the recombinant DNA techniques are reported.The synthetic peptide (I), like the polyclonal and monoclonal antipeptide antibodies are particularly suitable for the early diagnosis of hepatocellular carcinoma and of teratocarcinoma.
    Type: Grant
    Filed: February 13, 1992
    Date of Patent: April 27, 1993
    Assignee: Sclavo S.p.A.
    Inventors: Mario F. Tecce, Marzia M. Giuliani, Sterfano Ricci, Giulio Rttil, Benedetto Terrana
  • Synthetic peptide endowed with immunological activity, capable of inducing the production of antibodies with a high specificity towards alpha-fetoprotein, and their use in the diagnostic field
    Patent number: 5130415
    Abstract: A synthetic peptide endowed with immunological activity is disclosed, which is capable of inducing in mammals the formation of anti-peptide antibodies capable of recognizing human alpha-fetoprotein and of reacting with it, and incapable of recognizing albumin or its degradation products, with said peptide being essentially constituted by the aminoacidic sequence of formula (I), corresponding to 38-119 region of human alpha-fetoprotein.Furthermore, the methods and means for preparing said peptide by means of the recombinant DNA techniques are reported.The synthetic peptide (I), like the polyclonal and monoclonal antipeptide antibodies are particularly suitable for the early diagnosis of hepatocellular carcinoma and of teratocarcinoma.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: July 14, 1992
    Assignee: Sclavo S.p.A.
    Inventors: Mario F. Tecce, Marzia M. Giuliani, Stefano Ricci, Giulio Ratti, Benedetto Terrana