Patents by Inventor Mario Jose Abdalla Saad

Mario Jose Abdalla Saad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-anilinoquinazoline derivatives with adenosine-kinase inhibitor properties
    Patent number: 8513267
    Abstract: The present invention relates to the use of 4-anilinoquinazoline derivatives as adenosine-kinase inhibitors. The present invention also relates to a method for protecting tissues and organs like heart, brain and kidneys affected by ischemia, and for treating heart insufficiency, myocardium infarct, arrhythmia, arterial hypertension, atherosclerosis, coronary artery restenosis after angioplasty, chronic renal insufficiency, cerebral vascular accident, and chronic inflanunatory diseases (e.g., rheumatoid arthritis). The present invention also relates to the compound 6,7-dimethoxy-4-(3?-N?,N?-dimethylaminoanilino)quinazoline, or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising it and use of such compound in the manufacture of a medicament for treating or preventing diseases or conditions that are benefited from the adenosine-kinase inhibition.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: August 20, 2013
    Assignee: Universidade Estadual de Campinas-Unicamp
    Inventors: Kleber Gomes Franchini, Mario Jose Abdalla Saad, Roberto Rittner Neto, Rodrigo Miguel Marin, Silvana Aparecida Rocco