Abstract: The present invention provides an immune effector cell that comprises a chimeric antigen receptor (CAR) specific for a tag of a tagged polypeptide, wherein said polypeptide binds to an antigen of a target cell, and a chimeric costimulatory receptor (CCR) specific for a further antigen. The CCR is not able to mediate said immune response on its own but boosts the immune response of said immune effector cell triggered by the CAR.

Abstract: A drive with an electric motor and transmission connected to the electric motor at a drive shaft. Transmission has gears with different transmission ratios. The transmission performs a shifting process in which a coupling of the drive shaft, driven by the electric motor rotating at a first rotational speed, to the output shaft via a first gear with a first transmission ratio is first released, whereby the drive shaft is no longer rotationally coupled to the output shaft, after which the drive shaft is rotationally coupled to the output shaft via a second gear with a second transmission ratio. An electric synchronizing device is provided to change a rotational speed of the electric motor to a second rotational speed for a duration of the shifting process.

Abstract: A drive with an electric motor and transmission connected to the electric motor at a drive shaft. Transmission has gears with different transmission ratios. The transmission performs a shifting process in which a coupling of the drive shaft, driven by the electric motor rotating at a first rotational speed, to the output shaft via a first gear with a first transmission ratio is first released, whereby the drive shaft is no longer rotationally coupled to the output shaft, after which the drive shaft is rotationally coupled to the output shaft via a second gear with a second transmission ratio. An electric synchronizing device is provided to change a rotational speed of the electric motor to a second rotational speed for a duration of the shifting process.

Abstract: An inner part for a refrigerating device, such as an inner wall, a refrigerating item support, or similar item ideally should be easy to clean. At least a surface of the inner part is provided with effective protection against microbes and/or fungi. Because the inner part inhibits the growth of microbes and/or fungi, it is easier to clean and maintain.

Abstract: An ice-making device for a refrigerator or freezer comprises: an ice-making tray having an upper side, a lower side, a longitudinal direction and a transverse direction of said tray, wherein said ice-making tray is mounted so as to be rotatable about a first axis of rotation which is parallel to the longitudinal direction of the tray; a collecting container arranged underneath the ice-making tray for catching ice which falls out of said ice-making tray when the latter is in an emptying rotational position; a wall structure which, when the ice-making tray is in an ice-making rotational position, delimits a first air duct which runs underneath said ice-making tray and is open towards the underside of said tray, wherein said first air duct runs in the longitudinal direction of the tray and extends over substantially the entire length of the ice-making tray, wherein the wall structure has at least one wall element which, when the ice-making tray is in the ice-making rotational position, projects into a falling tr

Abstract: An inner part for a refrigerating device, such as an inner wall, a refrigerating item support, or similar item ideally should be easy to clean. At least a surface of the inner part is provided with effective protection against microbes and/or fungi. Because the inner part inhibits the growth of microbes and/or fungi, it is easier to clean and maintain.

Abstract: A refrigerating unit includes a cooling chamber, a storage compartment removably guided within the chamber as far as a closing position, and a disengagement device. The chamber has a parallel-guide disposed on its sides. The guide has a mating toothed configuration, two rollers rigidly coupled, lying opposite each other, and each having an external toothed configuration with a pitch circle diameter to be rollingly coupled to the mating toothed configuration. The guide has an end section reached by the rollers near the closing position. One of the mating toothed configuration and the rollers is positionally fixed. The disengagement device disengages the mating toothed configuration from the external toothed configuration of the rollers and is at the end section and has a disengagement length compensating for oblique positioning of the compartment in and counter to a movement direction arising from an offset of the rollers along the mating toothed configuration.

Abstract: A refrigerating unit includes a cooling chamber, a storage compartment removably guided within the chamber as far as a closing position, and a disengagement device. The chamber has a parallel-guide disposed on its sides. The guide has a mating toothed configuration, two rollers rigidly coupled, lying opposite each other, and each having an external toothed configuration with a pitch circle diameter to be rollingly coupled to the mating toothed configuration. The guide has an end section reached by the rollers near the closing position. One of the mating toothed configuration and the rollers is positionally fixed. The disengagement device disengages the mating toothed configuration from the external toothed configuration of the rollers and is at the end section and has a disengagement length compensating for oblique positioning of the compartment in and counter to a movement direction arising from an offset of the rollers along the mating toothed configuration.

Abstract: A refrigerating unit includes a cooling chamber, a storage compartment removably guided within the chamber as far as a closing position, and a disengagement device. The chamber has a parallel-guide disposed on its sides. The guide has a mating toothed configuration, two rollers rigidly coupled, lying opposite each other, and each having an external toothed configuration with a pitch circle diameter to be rollingly coupled to the mating toothed configuration. The guide has an end section reached by the rollers near the closing position. One of the mating toothed configuration and the rollers is positionally fixed. The disengagement device disengages the mating toothed configuration from the external toothed configuration of the rollers and is at the end section and has a disengagement length compensating for oblique positioning of the compartment in and counter to a movement direction arising from an offset of the rollers along the mating toothed configuration.

Abstract: A refrigerating unit includes a cooling chamber, a storage compartment removably guided within the chamber as far as a closing position, and a disengagement device. The chamber has a parallel-guide disposed on its sides. The guide has a mating toothed configuration, two rollers rigidly coupled, lying opposite each other, and each having an external toothed configuration with a pitch circle diameter to be rollingly coupled to the mating toothed configuration. The guide has an end section reached by the rollers near the closing position. One of the mating toothed configuration and the rollers is positionally fixed. The disengagement device disengages the mating toothed configuration from the external toothed configuration of the rollers and is at the end section and has a disengagement length compensating for oblique positioning of the compartment in and counter to a movement direction arising from an offset of the rollers along the mating toothed configuration.