Patents by Inventor MARIO LEONARDO SQUADRITO

MARIO LEONARDO SQUADRITO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered antigen presenting cells and uses thereof
    Patent number: 11591407
    Abstract: The present invention relates to engineered extra-cellular vesicle internalizing receptors that have the ability to enhance uptake, processing, and presentation to T-cells of tumor-associated antigens by an antigen-presenting cell. It further relates to vectors or antigen presenting cells expressing said receptors, composition and uses thereof for the prevention and/or treatment of a cancer.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: February 28, 2023
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPPFL)
    Inventors: Michele De Palma, Mario Leonardo Squadrito
  • ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF
    Publication number: 20190062450
    Abstract: The present invention relates to engineered extra-cellular vesicle internalizing receptors that have the ability to enhance uptake, processing, and presentation to T-cells of tumor-associated antigens by an antigen-presenting cell. It further relates to vectors or antigen presenting cells expressing said receptors, composition and uses thereof for the prevention and/or treatment of a cancer.
    Type: Application
    Filed: February 1, 2017
    Publication date: February 28, 2019
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: MICHELE DE PALMA, MARIO LEONARDO SQUADRITO