Patents by Inventor Mario Losen

Mario Losen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of effector-function-deficient antibodies for treatment of auto-immune diseases
    Patent number: 9181344
    Abstract: The invention relates to the treatment of autoimmune diseases and disorders, in particular myasthenia gravis, by administration of effector-function-deficient antibodies, wherein said effector-function-deficient antibodies are capable of competing with one or more of the auto-antibodies involved in mediating the antibody-mediated auto-immune disease or disorder for binding to a target auto-antigen.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: November 10, 2015
    Assignee: GENMAB A/S
    Inventors: Mario Losen, Pilar Martinez-Martinez, Marc H. De Baets, Yvo Graus, Janine Schuurman, Paul Parren
  • USE OF EFFECTOR-FUNCTION-DEFICIENT ANTIBODIES FOR TREATMENT OF AUTO-IMMUNE DISEASES
    Publication number: 20090317382
    Abstract: The invention relates to the treatment of autoimmune diseases and disorders, in particular myasthenia gravis, by administration of effector-function-deficient antibodies, wherein said effector-function-deficient antibodies are capable of competing with one or more of the auto-antibodies involved in mediating the antibody-mediated auto-immune disease or disorder for binding to a target auto-antigen.
    Type: Application
    Filed: December 15, 2006
    Publication date: December 24, 2009
    Applicant: GENMAB A/S
    Inventors: Mario Losen, Pilar Martinez-Martinez, Marc H. De Baets, Yvo Graus, Janine Schuurman, Paul Parren