Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.

Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.

Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.

Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.

Abstract: A prosthetic device for controlling urinary continence is disclosed. The device has an opening pressure that varies in response to changes in physiologic parameters. The device can be controlled by the patient voluntarily without manual intervention. An introducer for transurethrally introducing the device is also disclosed. In addition, a nonsurgical or minimally invasive method of positioning the device for maintaining urinary continence is disclosed.

Abstract: A prosthetic device for controlling urinary continence is disclosed. The device has an opening pressure that varies in response to changes in physiologic parameters. The device can be controlled by the patient voluntarily without manual intervention. A nonsurgical method of maintaining urinary continence is also disclosed.

Abstract: A prosthetic device for controlling urinary continence is disclosed. The device has an opening pressure that varies in response to changes in physiologic parameters. The device can be controlled by the patient voluntarily without manual intervention. An introducer for transurethrally introducing the device is also disclosed. In addition, a nonsurgical or minimally invasive method of positioning the device for maintaining urinary continence is disclosed.

Abstract: A prosthetic device for controlling urinary continence is disclosed. The device has an opening pressure that varies in response to changes in physiologic parameters. The device can be controlled by the patient voluntarily without manual intervention. An introducer for transurethrally introducing the device is also disclosed. In addition, a nonsurgical or minimally invasive method of positioning the device for maintaining urinary continence is disclosed.

Abstract: A prosthetic device for controlling urinary continence is disclosed. The device has an opening pressure that varies in response to changes in physiologic parameters. The device can be controlled by the patient voluntarily without manual intervention. A nonsurgical method of maintaining urinary continence is also disclosed.

Abstract: An ultrasonic imaging probe includes a probe guide assembly, an ultrasonic transducer fixed to the distal end of the probe guide assembly, and electrical cabling housed within the probe guide assembly and operatively connected to the transducer for sending electrical pulse/signals to/from the transducer. The transducer is of a type which emits/receives ultrasonic waves along a path parallel to the elongate axis of the probe. The ultrasonic waves are directed radially of the probe by means of a reflector element which is distally spaced from the transducer along the probe's axis by a dimension sufficient to remove "dead space"(i.e., an area where ultrasonic imaging is not possible) radially of the catheter. An inductor coil (which tunes the transducer to the electrical cabling) is coaxially housed within the probe guide assembly closely adjacent the transducer and is electrically connected in series thereto.

Abstract: An array of miniature ultrasound crystals mounted on preassembled subassembly which is, in turn, mounted on a small lumen catheter provides dimensional and other quantitative information relating to arterial wall geometry and character at disease or obstruction sites. Balloons also mounted to the catheter make it possible to use the catheter for the angioplasty (PCTA) procedure while actually imaging, in real time, the artery being dilatated and unblocked by the procedure. Efficient, highly miniature transducers are presented along with several different configurations for catheter structure containing fluid lumen, through-lumen, and electrical microcable assemblies for conducting electrical signals to and from the transducers.