Patents by Inventor Mario Maio

Mario Maio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing of inorganic particulate material
    Patent number: 10577250
    Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: March 3, 2020
    Assignee: Merck Patent GmbH
    Inventors: Mario Maio, Eugenia Breininger, Karin Cabrera Perez, Ulrich Lang, Benjamin Peters, Thomas Puchert, Christoph Saal, Michael Schulz
  • Microspheres of pancreatic enzymes with high stability and production method thereof
    Patent number: 9884025
    Abstract: The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: February 6, 2018
    Assignee: APTALIS PHARMA S.R.L.
    Inventor: Mario Maio
  • PROCESS FOR PRODUCING OF INORGANIC PARTICULATE MATERIAL
    Publication number: 20170049892
    Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Applicant: Merck Patent GmbH
    Inventors: Mario Maio, Eugenia Breininger, Karin Cabrera Perez, Ulrich Lang, Benjamin Peters, Thomas Puchert, Christoph Saal, Michael Schulz
  • Process for producing inorganic particulate material
    Patent number: 9517268
    Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: December 13, 2016
    Assignee: MERCK PATENT GMBH
    Inventors: Mario Maio, Eugenia Breininger, Karin Cabrera Perez, Ulrich Lang, Benjamin Peters, Thomas Puchert, Christoph Saal, Michael Schulz
  • MICROSPHERES OF PANCREATIC ENZYMES WITH HIGH STABILITY AND PRODUCTION METHOD THEREOF
    Publication number: 20160120815
    Abstract: The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.
    Type: Application
    Filed: November 30, 2015
    Publication date: May 5, 2016
    Inventor: Mario MAIO
  • Microspheres of pancreatic enzymes with high stability and production method thereof
    Patent number: 9259393
    Abstract: The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: February 16, 2016
    Assignee: Aptalis Pharma S.R.L.
    Inventor: Mario Maio
  • PROCESS FOR PRODUCING INORGANIC PARTICULATE MATERIAL
    Publication number: 20140336274
    Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
    Type: Application
    Filed: April 25, 2012
    Publication date: November 13, 2014
    Applicant: MERCK PATENT GMBH
    Inventors: Mario Maio, Eugenia Breininger, Karin Cabrera Perez, Ulrich Lang, Benjamin Peters, Thomas Puchert, Christoph Saal, Michael Schulz
  • Oral pharmaceutical composition of anilinopyrimidine, preparation and use thereof
    Patent number: 8277839
    Abstract: An oral pharmaceutical composition comprising a capsule dosage form containing a liquid fill composition including an anilinopyrimidine derivative of Formula (I) and a pharmaceutically acceptable excipient selected from the group consisting of polyethylene glycol, a glyceryl ester of capric acid or a mixture thereof. The liquid fill composition is formulated in a hard gelatin capsules and can be used for the preparation of a medicament for the treatment of cancer in particular AML.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: October 2, 2012
    Assignee: Ares Trading S.A.
    Inventors: Santa Fabiano, Mario Maio
  • Benzothiazole formulations and use thereof
    Patent number: 7838522
    Abstract: The present invention is related to macrogol glyceride pharmaceutical formulations containing benzothiazole derivatives. In particular, the invention is related to benzothiazole stearoyl macrogol pharmaceutical formulations, method of preparation and use thereof.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: November 23, 2010
    Assignee: Ares Trading S.A.
    Inventors: Pierandrea Esposito, Daniela Chicco, Luca Donati, Andrea Leonardi, Stefania Bertero, Jean-Pierre Gotteland, Pascale Gaillard, Isabelle Jeanclaude-Etter, Simone Grandolini, Mario Maio
  • Oral Pharmaceutical Composition of Anilinopyrimidine, Preparation and Use Thereof
    Publication number: 20090324711
    Abstract: An oral pharmaceutical composition comprising a capsule dosage form containing a liquid fill composition including an anilinopyrimidine derivative of Formula (I) and a pharmaceutically acceptable excipient selected from the group consisting of polyethylene glycol, a glyceryl ester of capric acid or a mixture thereof. The liquid fill composition is formulated in a hard gelatin capsules and can be used for the preparation of a medicament for the treatment of cancer in particular AML.
    Type: Application
    Filed: July 5, 2007
    Publication date: December 31, 2009
    Applicant: Ares Trading S.A.
    Inventors: Santa Fabiano, Mario Maio
  • PROCESS AND APPARATUS FOR COOLING AND ATOMIZING LIQUID OR PASTY-LIKE SUBSTANCES
    Publication number: 20090211265
    Abstract: A process and an apparatus for the rapid cooling and atomization of liquid or pasty substances, in particular even relatively small amounts of liquid or pasty substances being able to be cooled and atomized economically. Both process and apparatus are particularly useful in the pharmaceutical industry for preparing injectable microparticles of polymer or lipid matrices suitable for the incorporation of active ingredients.
    Type: Application
    Filed: August 21, 2008
    Publication date: August 27, 2009
    Applicants: LABORATOIRES SERONO S.A., MESSER ITALIA S.P.A
    Inventors: Mario MAIO, Daniela Chicco, Luca Donati, Pierandrea Esposito, Leonardo Galli, Mauro Menegoli
  • Benzothiazole Formulations and Use Thereof
    Publication number: 20080051397
    Abstract: The present invention is related to macrogol glyceride pharmaceutical formulations containing benzothiazole derivatives. In particular, the invention is related to benzothiazole stearoyl macrogol pharmaceutical formulations, method of preparation and use thereof.
    Type: Application
    Filed: November 16, 2005
    Publication date: February 28, 2008
    Applicant: ARES TRADING S.A.
    Inventors: Pierandrea Esposito, Daniela Chicco, Luca Donati, Andrea Leonardi, Stefania Bertero, Jean-Pierre Gotteland, Pascale Gaillard, Isabelle Jeanclaude-Etter, Simone Grandolini, Mario Maio
  • Process and apparatus for cooling and atomizing liquid or pasty-like substances
    Publication number: 20070079629
    Abstract: A process and an apparatus for the rapid cooling and atomization of liquid or pasty substances, in particular even relatively small amounts of liquid or pasty substances being able to be cooled and atomized economically. Both process and apparatus are particularly useful in the pharmaceutical industry for preparing injectable microparticles of polymer or lipid matrices suitable for the incorporation of active ingredients.
    Type: Application
    Filed: October 27, 2004
    Publication date: April 12, 2007
    Applicants: LABORATORIES SERONO S.A., MESSER ITALIA S.P.A.
    Inventors: Mario Maio, Daniela Chicco, Luca Donati, Pierandrea Esposito
  • Microspheres of pancreatic enzymes with high stability and production method thereof
    Publication number: 20040101562
    Abstract: The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.
    Type: Application
    Filed: May 14, 2003
    Publication date: May 27, 2004
    Inventor: Mario Maio