Patents by Inventor Mario Moscarello

Mario Moscarello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof
    Patent number: 9908853
    Abstract: The present application relates to imidazolidinecliones, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions characterized by or associated with the hypercitrullination of proteins by peptidyl arginine deiminase (PAD) enzymes. In particular, the present application includes compounds of Formula I, and compositions and uses thereof: (I).
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: March 6, 2018
    Assignees: THE HOSPITAL FOR SICK CHILDREN, UNIVERSITY HEALTH NETWORK
    Inventors: Lakshmi Kotra, Mario Moscarello
  • INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF
    Publication number: 20150252006
    Abstract: The present application relates to imidazolidinecliones, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions characterized by or associated with the hypercitrullination of proteins by peptidyl arginine deiminase (PAD) enzymes. In particular, the present application includes compounds of Formula I, and compositions and uses thereof: (I).
    Type: Application
    Filed: August 1, 2013
    Publication date: September 10, 2015
    Applicants: The Hospital For Sick Children, University Health Network
    Inventors: Lakshmi Kotra, Mario Moscarello