Patents by Inventor Mario Paglialunga Paradisi

Mario Paglialunga Paradisi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metalloproteinase inhibitors, their therapeutic use and process for the production of the starting compound in the synthesis thereof
    Patent number: 6339160
    Abstract: Objects of the present invention are compounds of a peptido-mimetic character having the capacity of acting as inhibitors of metalloproteinases produced by venom of snake, and of other metalloproteinases of human origin which have been put in relation with various pathologies in man, including tumoral growth and metastatization, aterosclerosis, multiple sclerosis, Alzheimer's disease, osteoporosis, hypertension, rheumatoid arthritis and other inflammatory diseases. Object of the present invention is also the procedure for the production of diethylester of (1)-phosphotryptophan, as an initial product necessary to synthesize all compounds mentioned above.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: January 15, 2002
    Assignees: Polifarma S.p.A., Consiglio Nazionale Delle Ricerche
    Inventors: Vincenzo Politi, Enrico Gavuzzo, Carlo Gallina, Giovanni Di Stazio, Silvana D'Alessio, Antonio Sella, Cinzia Piazza, Cesare Giordano, Barbara Gorini, Gabriella Panini, Mario Paglialunga Paradisi, Maurizio Cirilli, Giorgio Pochetti, Fernando Mazza