Patents by Inventor Mario SECHI

Mario SECHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10781183
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: September 22, 2020
    Assignees: The Regents of the University of Michigan, UNIVERSITA DEGLI STUDI DI SASSARI
    Inventors: Nouri Neamati, Mario Sechi
  • Publication number: 20190308942
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.
    Type: Application
    Filed: March 7, 2017
    Publication date: October 10, 2019
    Applicants: The Regents of the University of Michigan, UNIVERSITA DEGLI STUDI DI SASSARI
    Inventors: Nouri NEAMATI, Mario SECHI