Patents by Inventor Mario Serio

Mario Serio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic Method For The Forecasting Of Transplanted Organ Loosing
    Publication number: 20080009023
    Abstract: It is described a diagnostic method which allows to establish the risks of rejection of a transplanted organ by measuring the pre-transplant concentration of Mig in the serum of a patient to be submitted to transplantation.
    Type: Application
    Filed: November 24, 2005
    Publication date: January 10, 2008
    Inventors: Paola Romagnani, Mario Rotondi, Mario Serio
  • Pharmaceutical preparations containing thiazolidinediones showing new therapeutic indications
    Publication number: 20060287372
    Abstract: The present invention refers to new therapeutic applications of pharmaceutical formulations containing, as active principles, thiazolidinediones.
    Type: Application
    Filed: March 2, 2004
    Publication date: December 21, 2006
    Inventors: Andrea Galli, Paola Romagnani, Mario Serio, Calogero Surrenti
  • Benzo(C)quinolizine derivatives and their use as 5?-reductases inhibitors
    Patent number: 6962925
    Abstract: A fully and partially reduced benzo(c)quinolizine compound of formula (1):
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: November 8, 2005
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio
  • Process for the synthesis of (1-H)-benzo[c]quinolizin-3-ones derivatives
    Patent number: 6723850
    Abstract: The present invention refers to a process for the preparation of (1H)-benzo[c]quinolizin-3-ones derivatives of general formula (I) which involves only three steps and the use, as starting products, of commercially available, or easily preparable, compounds. The compounds of formula (I) are useful as inhibitors of 5&agr;-reductases.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: April 20, 2004
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio, Ernesto Occhiato
  • Benzo[C] quinolizine derivatives, their preparation and use as 5&agr;-reductases inhibitors
    Patent number: 6555549
    Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I) their pharmaceutically acceptable salts or esters, processes for their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: April 29, 2003
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio
  • Benzo[c]quinolizine derivatives, their preparation and use as 5&agr;-reductases inhibitors
    Patent number: 6552034
    Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I) their pharmaceutically acceptable salts or esters, processes for their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: April 22, 2003
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio
  • Use of benzo[C]quinolizine derivatives as plant growth regulators
    Patent number: 6514912
    Abstract: Disclosed are compositions of benzo(c)quinolizine derivatives and methods for promoting plant and seed growth. The compounds are benzo[c]quinolizine derivatives which exert an inhibiting effect on the 5-alpha-reductase enzymes. The compounds selectively affect the growth of plants, improving morphogenesis and development of commercially useful plants while acting as herbicides to inhibit weed development.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: February 4, 2003
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio
  • Benzo[c]quinolizine derivatives, their preparation and use as 5alpha-reductases inhibitors
    Publication number: 20010047098
    Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I) 1
    Type: Application
    Filed: June 25, 2001
    Publication date: November 29, 2001
    Inventors: Antonio Guarna, Mario Serio
  • Benzo [c] quinolizine derivatives, their preparation and use as 5alpha-reductases inhibitors
    Publication number: 20010044542
    Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I) 1
    Type: Application
    Filed: June 25, 2001
    Publication date: November 22, 2001
    Inventors: Antonio Guarna, Mario Serio
  • Benzo[c]quinolizine derivatives, their preparation and use as 5&agr;-reductases inhibitors
    Patent number: 6303622
    Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I) their pharmaceutically acceptable salts or esters, processes for their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 29, 1998
    Date of Patent: October 16, 2001
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Antonio Guarna, Mario Serio