Patents by Inventor Mario Sznol

Mario Sznol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination therapy comprising cloretazine
    Patent number: 7605137
    Abstract: This invention provides a method for treating tumor in a subject comprising administering to the subject an effective amount of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. This invention also provides a method for inhibiting tumor cell growth comprising contacting the tumor cell with effective amounts of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. The present invention relates to the treatment of cancer, comprising administering to a subject in need thereof an effective amount of VNP40101M in combination with a nucleoside.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: October 20, 2009
    Assignee: Vion Pharmaceuticals, Inc.
    Inventors: Ivan King, Mario Sznol, Michael Belcourt, Li-Mou Zheng
  • Combination Therapy Comprising Cloretazine
    Publication number: 20080025984
    Abstract: This invention provides a method for treating tumor in a subject comprising administering to the subject an effective amount of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. This invention also provides a method for inhibiting tumor cell growth comprising contacting the tumor cell with effective amounts of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. The present invention relates to the treatment of cancer, comprising administering to a subject in need thereof an effective amount of VNP40101M in combination with a nucleoside.
    Type: Application
    Filed: March 25, 2005
    Publication date: January 31, 2008
    Inventors: Ivan King, Mario Sznol, Michael Belcourt, Li-Mou Zheng
  • Antiviral agents and methods of treating viral infections
    Publication number: 20050261251
    Abstract: The present invention relates to methods of treating viral or fungal infections using 3-aminopyridine-2-carboxyaldehyde thiosemicarbazone (3-AP) and 3-amino-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-AMP) and its prodrug forms and to pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: March 30, 2005
    Publication date: November 24, 2005
    Applicants: Vion Pharmaceuticals, Inc., Yale University
    Inventors: Ivan King, Terrance Doyle, Mario Sznol, Alan Sartorelli, Yung-chi Cheng
  • Antiviral agents and methods of treating viral infections
    Patent number: 6911460
    Abstract: The present invention relates to methods of treating viral or fungal infections using 3-aminopyridine-2-carboxyaldehyde thiosemicarbazone (3-AP) and 3-amino-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-AMP) and its prodrug forms and to pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: June 28, 2005
    Assignees: Vion Pharmaceuticals, Inc., Yale University
    Inventors: Ivan C. King, Terrance W. Doyle, Mario Sznol, Alan C. Sartorelli, Yung-Chi Cheng
  • Antiviral agents and methods of treating viral infections
    Publication number: 20020188011
    Abstract: The present invention relates to methods of treating viral or fungal infections using 3-aminopyridine-2-carboxyaldehyde thiosemicarbazone (3-AP) and 3-amino-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-AMP) and its prodrug forms and to pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: April 18, 2002
    Publication date: December 12, 2002
    Inventors: Ivan C. King, Terrance W. Doyle, Mario Sznol, Alan C. Sartorelli, Yung-Chi Cheng