Patents by Inventor Mario T. Philipp

Mario T. Philipp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuronal Cell Propagation Using Rotating Wall Vessel
    Publication number: 20080274543
    Abstract: The present invention provides methods of propagating transformed neurons in a simulated microgravity environment generated by a rotating wall vessel (“3-D culture”) so that the phenotype of the transformed neurons so cultured becomes closer to that of non-transformed neurons (primary neurons) and less like the phenotype of transformed neurons cultured via standard cell culture techniques (“2-D culture”).
    Type: Application
    Filed: May 1, 2008
    Publication date: November 6, 2008
    Applicant: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
    Inventors: Mario T. Philipp, Cheryl A. Nickerson, Tereance A. Myers
  • Surface antigens and proteins useful in compositions for the diagnosis and prevention of Lyme disease
    Publication number: 20040067517
    Abstract: A novel isolated surface antigen, which is expressed in vitro by spirochetes of Borrelia garinii strain IP90, is characterized by a relative molecular mass of 39.5 kDa and the ability to induce antibodies which kill spirochetes of the B. burgdorferi sensu lato strain IP90 by ADCK in vitro. Novel B. garinii cassette string protein or fragments thereof are also useful, as is the P39.5 protein in diagnosing Lyme disease and in compositions for treatment or prophylaxis thereof.
    Type: Application
    Filed: August 1, 2003
    Publication date: April 8, 2004
    Applicant: The Administrators of the Tulane Educational Fund
    Inventor: Mario T. Philipp
  • Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease
    Patent number: 6660274
    Abstract: A novel isolated Borrielia burgdorferi sensu lato surface antigen is characterized by a relative molecular mass of 39.5 kDa. This antigen is expressed in vitro by spirochetes of a B. burgdorferi sensu lato strain. This antigen induces antibodies which kill spirochetes of a B. burgdorferi sensu lato strain by ADCK in vitro. Novel Borrelia cassette string protein or fragments thereof are also useful, as is the P39.5 protein in diagnosing Lyme disease and in compositions for treatment or prophylaxis thereof.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: December 9, 2003
    Assignee: The Administrators of the Tulane Educational Fund
    Inventor: Mario T. Philipp
  • SURFACE ANTIGENS AND PROTEINS USEFUL IN COMPOSITIONS FOR THE DIAGNOSIS AND PREVENTION OF LYME DISEASE
    Publication number: 20030059894
    Abstract: A novel isolated Borrielia burgdorferi sensu lato surface antigen is characterized by a relative molecular mass of 39.5 kDa. This antigen is expressed in vitro by spirochetes of a B. burgdorferi sensu lato strain. This antigen induces antibodies which kill spirochetes of a B. burgdorferi sensu lato strain by ADCK in vitro. Novel Borrelia cassette string protein or fragments thereof are also useful, as is the P39.5 protein in diagnosing Lyme disease and in compositions for treatment or prophylaxis thereof.
    Type: Application
    Filed: December 13, 1999
    Publication date: March 27, 2003
    Inventor: MARIO T. PHILIPP
  • Peptides and assays for the diagnosis of lyme disease
    Patent number: 6475492
    Abstract: A peptide consisting of an invariable 26-amino-acid-long region, named IR6, which is antigenically conversed among strains and species of the B. burgdorferi sensu lato complex, and immunodominant in both human and nonhuman primate hosts is described. This peptide is characterized by the sequence MKKDDQIAAAMVLRGMAKDGQFALKD (SEQ ID NO:1). This peptide is useful for rapid and specific diagnosis of Lyme disease, as are proteins containing this peptide and nucleic acid sequences encoding this peptide and these proteins.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: November 5, 2002
    Assignee: The Administrators of the Tulane Educational Fund
    Inventors: Mario T. Philipp, Fang Ting Liang