Patents by Inventor Marion Francis SETLIFF

Marion Francis SETLIFF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods Of Mapping Antigen Specificity To Antibody-Secreting Cells
    Publication number: 20230349919
    Abstract: The present disclosure provides antibody capture complexes and methods of capturing a target antibody secreted by an antibody secreting cell.
    Type: Application
    Filed: March 15, 2023
    Publication date: November 2, 2023
    Inventors: Brian Klotz, Seblewongel Asrat, Marion Francis Setliff, Andrea Vecchione, Joseph Cooper Devlin, Wei Keat Lim, Samuel Davis, Hang Song, Jamie Orengo, Gurinder Atwal, Matthew Sleeman, Wen-yi Lee, Gang Chen, Kristel Velez
  • METHODS FOR IDENTIFICATION OF LIGAND-BLOCKING ANTIBODIES AND FOR DETERMINING ANTIBODY POTENCY
    Publication number: 20230242966
    Abstract: The present disclosure relates to high-throughput systems and methods for the detection of ligand-blocking antibodies and for determining antibody potency.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 3, 2023
    Inventors: Marion Francis Setliff, Ivelin Stefanov Georgiev, Andrea Shiakolas, Kelsey PILEWSKI, Rohit VENKAT
  • METHODS FOR IDENTIFICATION OF LIGAND-BLOCKING ANTIBODIES AND FOR DETERMINING ANTIBODY POTENCY
    Publication number: 20220372551
    Abstract: The present disclosure relates to high-throughput systems and methods for the detection of ligand-blocking antibodies and for determining antibody potency.
    Type: Application
    Filed: July 22, 2021
    Publication date: November 24, 2022
    Inventors: Marion Francis Setliff, Ivelin Stefanov Georgiev, Andrea Shiakolas, Kelsey PILEWSKI, Rohit VENKAT
  • METHODS FOR IDENTIFICATION OF ANTIGEN BINDING SPECIFICITY OF ANTIBODIES
    Publication number: 20220315982
    Abstract: The present disclosure relates to a method for simultaneous detection of antigens and antigen specific antibodies. LIBRA-seq (Linking B Cell Receptor to Antigen specificity through sequencing) is developed to simultaneously recover both antigen specificity and paired heavy and light chain BCR sequence. LIBRA-seq is a next-generation sequencing-based readout for BCR-antigen binding interactions that utilizes oligonucleotides (oligos) conjugated to recombinant antigens.
    Type: Application
    Filed: September 4, 2020
    Publication date: October 6, 2022
    Inventors: Marion Francis SETLIFF, Ivelin Stefanov GEORGIEV, Andrea SHIAKOLAS
  • SYSTEMS AND METHODS FOR SIMULTANEOUS DETECTION OF ANTIGENS AND ANTIGEN SPECIFIC ANTIBODIES
    Publication number: 20210302422
    Abstract: The present disclosure relates to a system for simultaneous detection of antigens and antigen specific antibodies, and methods of use thereof.
    Type: Application
    Filed: July 26, 2019
    Publication date: September 30, 2021
    Inventors: Marion Francis SETLIFF, Ivelin Stefanov GEORGIEV, Andrea SHIAKOLAS