Patents by Inventor Marirosa Mora

Marirosa Mora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • proteins and nucleic acids
    Patent number: 8287884
    Abstract: The invention provides proteins from Staphylococcus aureus, including amino acid sequences and corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies, and as targets for antibiotics.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: October 16, 2012
    Assignee: Novartis AG
    Inventors: Vega Masignani, Marirosa Mora, Maria Scarselli
  • NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
    Publication number: 20120164166
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Application
    Filed: January 26, 2012
    Publication date: June 28, 2012
    Applicants: NOVARTIS AG, J. CRAIG VENTER INSTITUTE, INC.
    Inventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
    Publication number: 20120156236
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Application
    Filed: January 26, 2012
    Publication date: June 21, 2012
    Applicants: NOVARTIS AG, J. CRAIG VENTER INSTITUTE, INC.
    Inventors: Claire FRASER, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
    Publication number: 20120148616
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Application
    Filed: January 26, 2012
    Publication date: June 14, 2012
    Applicants: NOVARTIS AG, J. CRAIG VENTER INSTITUTE, INC.
    Inventors: Claire FRASER, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
    Publication number: 20120135024
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Application
    Filed: March 23, 2011
    Publication date: May 31, 2012
    Applicants: NOVARTIS AG, J. CRAIG VENTER INSTITUTE, INC.
    Inventors: Claire FRASER, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
    Publication number: 20120058143
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Applicant: NOVARTIS VACCINES & DIAGNOSTICS SRL
    Inventors: Vega MASIGNANI, Marirosa Mora, Maria Scarselli
  • STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
    Publication number: 20120052084
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 1, 2012
    Applicant: NOVARTIS VACCINES & DIAGNOSTICS SRL
    Inventors: Vega Masignani, Marirosa Mora, Maria Scarselli
  • STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
    Publication number: 20120020890
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Application
    Filed: October 4, 2011
    Publication date: January 26, 2012
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS SRL
    Inventors: Vega MASIGNANI, Marirosa Mora, Maria Scarselli
  • STREPTOCOCCUS PYOGENES CLASSIFICATION
    Publication number: 20110195409
    Abstract: The difference Lancefield T-serotypes correlate with the sequence of the pilus backbone protein (Pbp) in Streptococcus pyogenes (GAS). We have sequenced Pbp for over 50 GAS strains, representing the major disease-associated serotypes, and have identified 15 Pbp variants. These 15 variants have been shown to determine the specificity of the T-serotyping, such that sequencing of the Pbp from a given GAS strain reliably predicts that strain's T-serotype. thus the invention permits the t-serotype of a GAS strain to be determined based on genotype.
    Type: Application
    Filed: November 6, 2008
    Publication date: August 11, 2011
    Applicant: Novartis Vaccines and Diagnostics SRL
    Inventors: Guido Grandi, Marirosa Mora, John L. Telford, Chiara Zingaretti, Fabiana Falugi
  • STREPTOCOCCUS PNEUMONIAE PILUS ANTIGENS
    Publication number: 20110097360
    Abstract: Polypeptides from Streptococcus pneumoniae are described. In some aspects the polypeptides include pili polypeptides from a second pili island (pilus II island (INV1 04B)) identified in Streptococcus pneumoniae isolate INV1 04. In other aspects the polypeptides include pili polypeptides and non-pilus polypeptides from Streptococcus pneumoniae strains 23F, INV200, and OXC141 that are absent from Streptococcus pneumoniae isolate INV104. The polypeptides, including fragments and variants thereof, may be used in immunogenic compositions for prophylactic or therapeutic immunization against Streptococcus pneumoniae. The polypeptides are also disclosed to be used in compositions useful for the production of antibodies and immunostimulants. Also presented are methods of inhibiting Streptococcus pneumoniae, methods of treating Streptococcus pneumoniae infection, methods of identifying inhibitors of Streptococcus pneumoniae and methods for diagnosing/detecting Streptococcus pneumoniae infection.
    Type: Application
    Filed: May 23, 2008
    Publication date: April 28, 2011
    Inventors: Claudio Donati, Vega Masignani, Marirosa Mora, Monica Moschioni
  • IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA
    Publication number: 20100150943
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Gram positive Streptococcus serotypes and isolates. Adhesin island polypeptides of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS, GBS, and S. pneumococcal infections.
    Type: Application
    Filed: July 26, 2007
    Publication date: June 17, 2010
    Applicant: NOVARTIS AG
    Inventors: Guido Grandi, John Telford, Marirosa Mora, Cesira Galeotti, Daniela Rinaudo, Andrea Guido Oreste Manetti
  • STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
    Publication number: 20100055130
    Abstract: The invention provides proteins from Staphylococcus aureus, including amino acid sequences and corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies, and as targets for antibiotics.
    Type: Application
    Filed: October 6, 2009
    Publication date: March 4, 2010
    Applicant: Novartis AG
    Inventors: Vega Masignani, Marirosa Mora, Maria Scarselli
  • Staphylococcus aureus proteins and nucleic acids
    Publication number: 20100047267
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Application
    Filed: July 17, 2009
    Publication date: February 25, 2010
    Inventors: Vega Masignani, Marirosa Mora, Maria Scarselli
  • Antigenic meningococcal peptides
    Patent number: 7618636
    Abstract: WO99/36544 discloses a large number of proteins from Neisseria Meningitidis. The present invention relates to fragments of those proteins which comprise at least one antigenic determinant. Homologous sequences and proteins comprising these fragments are also disclosed.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: November 17, 2009
    Assignee: Novartis Vaccines And Diagnostics SRL
    Inventors: Vega Masignani, Vincenzo Scarlato, Maria Scarselli, Cesira L. Galeotti, Marirosa Mora
  • genomic sequences and methods of their use
    Patent number: 7612192
    Abstract: The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B. The proteins so obtained are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: November 3, 2009
    Assignees: Novartis Vaccines & Diagnostics, Inc., J. Craig Venter Institute
    Inventors: Claire Marie Fraser, Erin Kathleen Hickey, Jeremy D. Peterson, Herve Tettelin, Craig Ventor, Vega Masignani, Cesira Galeotti, Marirosa Mora, Giulio Ratti, Maria Scarselli, Vincenzo Scarlato, Rino Rappuoli, Mariagrazia Pizza, Guido Grandi
  • proteins and nucleic acids
    Patent number: 7608276
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: October 27, 2009
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventors: Vega Masignani, Marirosa Mora, Maria Scarselli
  • NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
    Publication number: 20090232820
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Application
    Filed: January 11, 2008
    Publication date: September 17, 2009
    Inventors: Claire FRASER, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • antigens and compositions
    Patent number: 7576176
    Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: August 18, 2009
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
  • Neisseria genomic sequences and methods of their use
    Publication number: 20070219347
    Abstract: The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B.
    Type: Application
    Filed: February 26, 2007
    Publication date: September 20, 2007
    Inventors: Claire Fraser, Erin Hickey, Jeremy Peterson, Herve Tettelin, J. Venter, Vega Masignani, Cesira Galeotti, Marirosa Mora, Giulio Ratti, Maria Scarselli, Vincenzo Scarlato, Rino Rappuoli, Mariagrazia Pizza, Guido Grandi
  • Antigenic neisserial peptides
    Publication number: 20070053926
    Abstract: WO99/24578 discloses a large number of proteins from Neisseria meningitidis and Neisseria gonorrhoeae. The present invention relates to fragments of those proteins which comprise at least one antigenic determinant. Homologous sequences and proteins comprising these fragments are also disclosed.
    Type: Application
    Filed: April 13, 2005
    Publication date: March 8, 2007
    Inventors: Vega Masignani, Vincenzo Scarlato, Maria Soarselli, Cesira Galeotti, Marirosa Mora