Patents by Inventor Marisa Lin Wong Medina

Marisa Lin Wong Medina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HMGCR isoforms in prediction of efficacy and identification of cholesterol-modulating compounds
    Patent number: 8084209
    Abstract: The present invention provides methods for assessing a subject's responsiveness to a HMGCR inhibitor therapy, and selection of a HMGCR inhibitor therapy based upon such methods. The invention further provides methods for identifying agents that modulate HMGCR activity, e.g., through modulating HMGCR mRNA splicing, while avoiding elevation of the statin-resistant isoform of HMGCR.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: December 27, 2011
    Assignee: Children's Hospital & Research Center Oakland
    Inventors: Marisa Lin Wong Medina, Ronald M. Krauss
  • Hmgcr isoforms in Prediction of Efficacy and Identification of Cholesterol-Modulating Compounds
    Publication number: 20080293054
    Abstract: The present invention provides methods for assessing a subject's responsiveness to a HMGCR inhibitor therapy, and selection of a HMGCR inhibitor therapy based upon such methods. The invention further provides methods for identifying agents that modulate HMGCR activity, e.g., through modulating HMGCR mRNA splicing, while avoiding elevation of the statin-resistant isoform of HMGCR.
    Type: Application
    Filed: July 21, 2006
    Publication date: November 27, 2008
    Inventors: Marisa Lin Wong Medina, Ronald M. Krauss