Patents by Inventor Marisa Montemartini

Marisa Montemartini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-ones as protein kinase inhibitors
    Patent number: 9145418
    Abstract: The present invention relates to substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives, of formula (I) which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: September 29, 2015
    Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Francesco Casuscelli, Elena Casale, Marisa Montemartini, Claudia Piutti
  • SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS
    Publication number: 20140243347
    Abstract: The present invention relates to substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.
    Type: Application
    Filed: October 4, 2012
    Publication date: August 28, 2014
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Francesco Casuscelli, Elena Casale, Marisa Montemartini, Claudia Piutti
  • Tryparedoxin, expression plasmid, process of preparation, method of use, test kit and pharmaceutical composition
    Publication number: 20050143559
    Abstract: The present invention provides novel enzymes, tryparedoxins, their isolation from Crithidia fasciculata, a method for the production thereof in genetically transformed bacteria, and their use as molecular targets for the discovery of trypanocidal drugs
    Type: Application
    Filed: October 12, 2004
    Publication date: June 30, 2005
    Inventors: Leopold Flohe, Everson Nogoceke, Henryk Kalisz, Marisa Montemartini
  • Tryparedoxin, expression plasmid, process of production, method of use, test kit, and pharmaceutical composition
    Publication number: 20030082202
    Abstract: The present invention provides novel enzymes, tryparedoxins, their isolation from Crithidia fasciculata, a method for the production thereof in genetically transformed bacteria, and their use as molecular targets for the discovery of trypanocidal drugs
    Type: Application
    Filed: July 12, 2002
    Publication date: May 1, 2003
    Inventors: Leopold Flohe, Everson Nogeceke, Henryk Kalisz, Marisa Montemartini
  • Tryparedoxin, expression plasmid, process of production, method of use, test kit, and pharmaceutical composition
    Patent number: 6432671
    Abstract: The present invention provides novel enzymes, tryparedoxins, their isolation from Crithidia fasciculata, a method for the production thereof in genetically transformed bacteria, and their use as molecular targets for the discovery of trypanocidal drugs.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: August 13, 2002
    Inventors: Leopold Flohé, Everson Nogoceke, Henryk Kalisz, Marisa Montemartini