Patents by Inventor Maristella Bernini

Maristella Bernini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230263804
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 24, 2023
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20220211713
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 7, 2022
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20220047522
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the anti-TB compound bedaquiline, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of a pathogenic mycobacterial infection.
    Type: Application
    Filed: September 8, 2021
    Publication date: February 17, 2022
    Inventors: Koenraad Jozef Lodewijk Marcel Andries, Maristella Bernini, Esther Dina Guido Basstanie
  • Patent number: 11141384
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the anti-TB compound bedaquiline, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of a pathogenic mycobacterial infection.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: October 12, 2021
    Assignee: Janssen Pharmaceutica NV
    Inventors: Koenraad Jozef Lodewijk Marcel Andries, Maristella Bernini, Esther Dina Guido Basstanie
  • Publication number: 20200171036
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 4, 2020
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20190381174
    Abstract: Disclosed are formulations/compositions comprising ibrutinib: as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: June 14, 2019
    Publication date: December 19, 2019
    Inventors: Maristella Bernini, Wenyu Dong, Rene Holm
  • Publication number: 20170252344
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 7, 2017
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20160287594
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 6, 2016
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht