Patents by Inventor MARIUS ADER

MARIUS ADER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTOGENETICALLY TRANSFORMED PHOTORECEPTOR PRECURSOR CELLS FOR THE USE IN THE TREATMENT OF RETINAL DEGENERATIVE DISEASES
    Publication number: 20200032203
    Abstract: The present invention relates to photoreceptor precursor cells comprising a heterologous nucleic acid encoding an optogenetic inhibitor. The present invention also relates to a pharmaceutical composition comprising photoreceptor precursor cells of the invention and a pharmaceutically acceptable excipient. The present invention relates to photoreceptor precursor cells or pharmaceutical composition of the invention for use in the treatment of a retinal degenerative disease, preferably a retinal degenerative disease related to a loss of function or death of photoreceptors. Finally, the present invention relates to a method for producing the photoreceptor precursor cells of the invention, comprising i) providing photoreceptor precursor cells; and ii) introducing into said precursor cells a nucleic acid encoding optogenetic inhibitor.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 30, 2020
    Inventors: JENS DUEBEL, MARIUS ADER, ANTOINE CHAFFIOL, MARCELA GARITA-HERNANDEZ, MARUSA LAMPIC, DENIZ DALKARA, OLIVIER GOUREAU, JOSÉ-ALAIN SAHEL