Patents by Inventor Marius Tiemen Roelof Kupier

Marius Tiemen Roelof Kupier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of polymorphisms in AFLP fragments using primer extension techniques
    Patent number: 7169552
    Abstract: The present invention relates to a method for determining the genotypes of polymorphic loci amplified in a mixture of restriction fragments, using an oligonucleotide sequence that is essentially complementary to part of the target restriction fragment, and located adjacent (upstream) to the polymorphism to be detected. The method involves contacting the mixture of restriction fragments with the oligonucleotide sequence under hybridization conditions, such that when the target restriction fragment is present, a hybrid is formed between the target restriction fragment and the oligonucleotide sequence.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: January 30, 2007
    Assignee: Keygene N.V.
    Inventors: Marius Tiemen Roelof Kupier, Hanneke Witsenboer