Patents by Inventor Marius Wagner

Marius Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated method for maintaining a clinical diagnostics system
    Patent number: 11287402
    Abstract: An analytical system including a mass spectrometer (MS) coupled to liquid chromatography (LC) via an ionization source (IS), and an automated method of maintaining the analytical system in a QC-compliant status are described. The method comprises determining a deviation of the analytical system from a QC-compliant status by determining a deviation of one or more predetermined parameters in an m/z spectrum above one or more predetermined thresholds, triggering an IS and/or MS maintenance procedure upon determining a deviation from the QC-compliant status, determining a return or a failed return to the QC-compliant status during and/or after the IS and/or MS maintenance procedure by determining a return or a failed return respectively of the one or more predetermined parameters in an m/z spectrum below the one or more predetermined thresholds, triggering another IS and/or MS maintenance procedure upon determining a failed return to the QC-compliant status.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: March 29, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Quint, Marian Roetzer, Florian Schweinberger, Benjamin Tiemann, Marius Wagner, Ralf Zimmermann
  • AUTOMATED METHOD FOR MANTAINING A CLINICAL DIAGNOSTICS SYSTEM
    Publication number: 20210181166
    Abstract: An analytical system including a mass spectrometer (MS) coupled to liquid chromatography (LC) via an ionization source (IS), and an automated method of maintaining the analytical system in a QC-compliant status are described. The method comprises determining a deviation of the analytical system from a QC-compliant status by determining a deviation of one or more predetermined parameters in an m/z spectrum above one or more predetermined thresholds, triggering an IS and/or MS maintenance procedure upon determining a deviation from the QC-compliant status, determining a return or a failed return to the QC-compliant status during and/or after the IS and/or MS maintenance procedure by determining a return or a failed return respectively of the one or more predetermined parameters in an m/z spectrum below the one or more predetermined thresholds, triggering another IS and/or MS maintenance procedure upon determining a failed return to the QC-compliant status.
    Type: Application
    Filed: December 7, 2020
    Publication date: June 17, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Quint, Marian Roetzer, Florian Schweinberger, Benjamin Tiemann, Marius Wagner, Ralf Zimmermann