Patents by Inventor Marja Liisa Alajoki

Marja Liisa Alajoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for continuous liquid flow in microscale channels using wicking
    Patent number: 6989128
    Abstract: Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of materials through a side channel and the use of an absorbent material to induce wicking in the channel system. The apparatus provided includes a prefabricated wick in the device to provide for flow rate control. Additional methods for determining velocity of a particle and cell incubation time are also provided.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: January 24, 2006
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Marja Liisa Alajoki, H. Garrett Wada, Robert S. Dubrow
  • Focusing of microparticles in microfluidic systems
    Patent number: 6592821
    Abstract: Methods and systems for particle focusing to increase assay throughput and sensitivity in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations, such as cells and various subcellular components are also provided. Integrated systems in which particles are focused and/or sorted are additionally included.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: July 15, 2003
    Assignee: Caliper Technologies Corp.
    Inventors: H. Garrett Wada, Anne R. Kopf-Sill, Marja Liisa Alajoki, J. Wallace Parce, Benjamin N. Wang, Andrea W. Chow, Robert S. Dubrow, Yevgeny Yurkovetsky, Javier Anibal Farinas
  • Focusing of microparticles in microfluidic systems
    Patent number: 6506609
    Abstract: Methods and systems for particle focusing to increase assay throughput in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations, such as cells and various subcellular components are also provided. Integrated systems in which particles are focused and/or sorted are additionally included.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: January 14, 2003
    Assignee: Caliper Technologies Corp.
    Inventors: H. Garrett Wada, Anne R. Kopf-Sill, Marja Liisa Alajoki, J. Wallace Parce, Benjamin N. Wang, Andrea W. Chow, Robert S. Dubrow
  • Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
    Publication number: 20020179445
    Abstract: Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of materials through a side channel and the use of an absorbent material to induce wicking in the channel system. The apparatus provided includes a prefabricated wick in the device to provide for flow rate control. Additional methods for determining velocity of a particle and cell incubation time are also provided.
    Type: Application
    Filed: May 8, 2002
    Publication date: December 5, 2002
    Applicant: Caliper Technologies Corp.
    Inventors: Marja Liisa Alajoki, H. Garrett Wada, Robert S. Dubrow
  • Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
    Patent number: 6416642
    Abstract: Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of materials through a side channel and the use of an absorbent material to induce wicking in the channel system. The apparatus provided includes a prefabricated wick in the device to provide for flow rate control. Additional methods for determining velocity of a particle and cell incubation time are also provided.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: July 9, 2002
    Assignee: Caliper Technologies Corp.
    Inventors: Marja Liisa Alajoki, H. Garrett Wada, Robert S. Dubrow