Patents by Inventor Marjie L. Hard

Marjie L. Hard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aripiprazole Dosing Strategy
    Publication number: 20220152021
    Abstract: The present invention relates to methods of treating schizophrenia using a combination of aripiprazole, aripiprazole lauroxil, and a nanoparticle dispersion of aripiprazole lauroxil.
    Type: Application
    Filed: February 4, 2022
    Publication date: May 19, 2022
    Inventors: Lisa L. von Moltke, Peter J. Weiden, Marjie L. Hard
  • Aripiprazole dosing strategy
    Patent number: 11273158
    Abstract: The present invention relates to methods of treating schizophrenia using a combination of aripiprazole, aripiprazole lauroxil, and a nanoparticle dispersion of aripiprazole lauroxil.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: March 15, 2022
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Lisa L. von Moltke, Peter J. Weiden, Marjie L. Hard
  • Aripiprazole Dosing Strategy
    Publication number: 20190298716
    Abstract: The present invention relates to methods of treating schizophrenia using a combination of aripiprazole, aripiprazole lauroxil, and a nanoparticle dispersion of aripiprazole lauroxil.
    Type: Application
    Filed: March 4, 2019
    Publication date: October 3, 2019
    Inventors: Lisa L. von Moltke, Peter J. Weiden, Marjie L. Hard
  • ARIPIPRAZOLE PRODRUG COMPOSITION
    Publication number: 20180318293
    Abstract: Described is a composition comprising (a) a population of particles of an aripiprazole prodrug having a volume based particle size (Dv50) of less than 1000 nm and (b) at least one surface stabilizer comprising an adsorbed component which is adsorbed on the surface of the aripiprazole prodrug particles and a free component available for solubilisation of the aripiprazole prodrug. The surface stabilizer to prodrug ratio provides the optimal quantity of free surface stabilizer for the purposes of producing a lead-in formulation. Also described are methods of treatment using the aforementioned composition.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 8, 2018
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Philip Cresswell, Sara Montminy Paquette, Magali Hickey, Kristopher Perkin, Greg Smith, Elaine Liversidge, Brian Steinberg, David Manser, Ryan Turncliff, Michael Palmieri, JR., Tarek Zeidan, Ethan P. Cash, Marjie L. Hard
  • Aripiprazole prodrug compositions
    Patent number: 10016415
    Abstract: Described is a composition comprising (a) a population of particles of an aripiprazole prodrug having a volume based particle size (Dv50) of less than 1000 nm and (b) at least one surface stabilizer comprising an adsorbed component which is adsorbed on the surface of the aripiprazole prodrug particles and a free component available for solubilization of the aripiprazole prodrug. The surface stabilizer to prodrug ratio provides the optimal quantity of free surface stabilizer for the purposes of producing a lead-in formulation. Also described are methods of treatment using the aforementioned composition.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: July 10, 2018
    Assignee: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Philip Cresswell, Sara Montminy Paquette, Magali Hickey, Kristopher Perkin, Greg Smith, Elaine Liversidge, Brian Steinberg, David Manser, Ryan Turncliff, Michael Palmieri, Jr., Tarek Zeidan, Ethan P. Cash, Marjie L. Hard
  • ARIPIPRAZOLE PRODRUG COMPOSITIONS
    Publication number: 20160045495
    Abstract: Described is a composition comprising (a) a population of particles of an aripiprazole prodrug having a volume based particle size (Dv50) of less than 1000 nm and (b) at least one surface stabilizer comprising an adsorbed component which is adsorbed on the surface of the aripiprazole prodrug particles and a free component available for solubilisation of the aripiprazole prodrug. The surface stabilizer to prodrug ratio provides the optimal quantity of free surface stabilizer for the purposes of producing a lead-in formulation. Also described are methods of treatment using the aforementioned composition.
    Type: Application
    Filed: August 17, 2015
    Publication date: February 18, 2016
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Philip CRESSWELL, Sara Montminy Paquette, Magali Hickey, Kristopher Perkin, Greg Smith, Elaine Liversidge, Brian Steinberg, David Manser, Ryan Turncliff, Michael Palmieri, Tarek Zeidan, Ethan P. Cash, Marjie L. Hard