Abstract: The present invention relates to the field of microvascular reconstruction surgery of bone defects. More specifically, the invention relates to a biological jaw regenerate and to methods of preparing said jaw regenerate. Furthermore, the invention relates to a method of reconstructing a jaw defect in a patient in need thereof.

Abstract: An arrangement for determining the position of a needle in an organ system and a method utilizing the arrangement in cosmetic treatment or cosmetic surgery. The arrangement (1) comprises a needle (2) with a distal tip (3), a measurement circuit (4) measuring the bioimpedance of tissues, a detection means (10) connected to the measurement circuit measuring bioimpedance and arranged to detect the progress of the distal tip (3) of the needle at a real-time basis from the bioimpedance measured from tissues. The arrangement (1) comprises at least two electrodes (16, 18, 21, 22) arranged at the distal tip (3) of the needle and connected to the measurement circuit (4). All the electrodes (16, 18, 21, 22) measuring impedance and needed for monitoring the progress of the distal tip (3) of the needle are arranged to the distal tip (3) of the needle.

Abstract: The present invention relates to a serum replacement formulation and to a culture medium suitable for the derivation, maintenance and differentiation of stem cells.