Patents by Inventor Marjoke Froukje DEBETS

Marjoke Froukje DEBETS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED AZADIBENZOCYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS
    Publication number: 20160107999
    Abstract: The invention relates to a substituted azadibenzocyclooctyne compound according to Formula (5): The invention also relates to a conjugate wherein a substituted azadibenzocyclooctyne according to the invention is conjugated to a label, and to the use of these conjugates for bioorthogonal labeling, imaging or modification of a target molecule, e.g. surface modification. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.
    Type: Application
    Filed: May 21, 2014
    Publication date: April 21, 2016
    Applicant: SynAffix B.V.
    Inventors: Marjoke Froukje DEBETS, Floris Petrus Johannes Theodorus RUTJES, Jan Cornelis Maria VAN HEST, Floris Louis VAN DELFT, Sander Sebastiaan VAN BERKEL