Patents by Inventor Mark A. Billadeau
Mark A. Billadeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12196749Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: July 29, 2020Date of Patent: January 14, 2025Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20210109100Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: July 23, 2020Publication date: April 15, 2021Applicant: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Patent number: 10935547Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: July 28, 2016Date of Patent: March 2, 2021Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20210055287Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: November 5, 2020Publication date: February 25, 2021Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20200355616Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 10753934Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: GrantFiled: February 1, 2018Date of Patent: August 25, 2020Assignee: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20180238882Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: February 1, 2018Publication date: August 23, 2018Applicant: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20180172595Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: February 16, 2018Publication date: June 21, 2018Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9921166Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: September 5, 2014Date of Patent: March 20, 2018Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9891221Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: GrantFiled: June 30, 2014Date of Patent: February 13, 2018Assignee: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20160356722Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: July 28, 2016Publication date: December 8, 2016Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9404881Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: February 3, 2014Date of Patent: August 2, 2016Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140378341Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: September 5, 2014Publication date: December 25, 2014Applicant: MESO SCALE TECHNOLOGIES, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140336070Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: June 30, 2014Publication date: November 13, 2014Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Patent number: 8852922Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: August 30, 2011Date of Patent: October 7, 2014Assignee: Meso Scale Technologies, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140274805Abstract: Materials and Methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.Type: ApplicationFiled: April 10, 2014Publication date: September 18, 2014Applicant: MESO SCALE TECHNOLOGIES LLCInventors: Jacob N. WOHLSTADTER, James L. WILBUR, George B. SIGAL, Mark T. MARTIN, Liang-Hong GUO, Alan FISCHER, Jon LELAND, Mark A. BILLADEAU, Larry R. HELMS, Ramin DARVARI
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Patent number: 8785201Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: GrantFiled: February 10, 2009Date of Patent: July 22, 2014Assignee: Meso Scale Technologies, LLCInventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20140151224Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: February 3, 2014Publication date: June 5, 2014Applicant: Meso Scale Technologies, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 8722323Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.Type: GrantFiled: November 2, 2010Date of Patent: May 13, 2014Assignee: Meso Scale Technologies LLPInventors: Jacob N. Wohlstadter, James L. Wilbur, George B. Sigal, Mark T. Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark A. Billadeau, Larry R. Helms, Ramin Darvari
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Patent number: 8641986Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: October 2, 2008Date of Patent: February 4, 2014Assignee: Meso Scale Technologies, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan