Patents by Inventor Mark A. Billadeau
Mark A. Billadeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230061508Abstract: Electrochemical cells and methods for their production are provided. In particular, multi-well assay plates including multi-electrode wells are provided. The multi-electrode wells contain multiple electrodes that are electrically isolated from one another, permitting the various electrodes of the various wells to be addressed in any suitable combination.Type: ApplicationFiled: August 12, 2022Publication date: March 2, 2023Inventors: Scott DOWDELL, Nicholas CARBONE, Charles CLINTON, Mark BILLADEAU, Manish KOCHAR, Nicholas FOX-LYON, Alexander TUCKER-SCHWARTZ, George SIGAL, Gisbert SPIELES, Jules VANDERSARL, Jacob WOHLSTADTER, Aaron LEIMKUEHLER, Jeffrey PETTINGILL, Leo TABAKIN, Bandele JEFFREY-COKER
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Publication number: 20220057362Abstract: An electrochemical cell includes a plurality of working electrode zones disposed, and defining a pattern, on a surface of the cell and at least one auxiliary electrode disposed on the surface. The auxiliary electrode may have a defined interfacial potential.Type: ApplicationFiled: August 20, 2021Publication date: February 24, 2022Inventors: Mark Billadeau, Nicholas Carbone, Charles Clinton, Scott Dowdell, Manish Kochar, Nicholas Fox-Lyon, Bandele Jeffrey-Coker, Alexander Tucker-Schwartz, George Sigal, Gisbert Spieles, Jules Vandersarl, Jacob Wohlstadter
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Publication number: 20210109100Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: July 23, 2020Publication date: April 15, 2021Applicant: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Patent number: 10955412Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.Type: GrantFiled: May 8, 2015Date of Patent: March 23, 2021Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Mark Billadeau, Paul Freese, Alan Kishbaugh, Gisbert Spieles, Nicholas Fox-Lyon
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Publication number: 20210063386Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.Type: ApplicationFiled: October 28, 2020Publication date: March 4, 2021Applicant: Meso Scale Technologies, LLC.Inventors: Mark BILLADEAU, Paul FREESE, Alan KISHBAUGH, Gisbert SPIELES, Nicholas FOX-LYON
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Patent number: 10935547Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: July 28, 2016Date of Patent: March 2, 2021Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20210055287Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: November 5, 2020Publication date: February 25, 2021Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20200355616Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 10753934Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: GrantFiled: February 1, 2018Date of Patent: August 25, 2020Assignee: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20180238882Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: February 1, 2018Publication date: August 23, 2018Applicant: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20180172595Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: February 16, 2018Publication date: June 21, 2018Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9921166Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: September 5, 2014Date of Patent: March 20, 2018Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9891221Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: GrantFiled: June 30, 2014Date of Patent: February 13, 2018Assignee: Meso Scale Technologies, LLC.Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Publication number: 20170241995Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.Type: ApplicationFiled: May 8, 2015Publication date: August 24, 2017Applicant: MESO SCALE TECHNOLOGIES, LLC.Inventors: Mark BILLADEAU, Paul FREESE, Alan KISHBAUGH, Gisbert SPIELES, Nicholas FOX-LYON
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Publication number: 20160356722Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: July 28, 2016Publication date: December 8, 2016Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Patent number: 9404881Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: February 3, 2014Date of Patent: August 2, 2016Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeffery D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140378341Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: ApplicationFiled: September 5, 2014Publication date: December 25, 2014Applicant: MESO SCALE TECHNOLOGIES, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140336070Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.Type: ApplicationFiled: June 30, 2014Publication date: November 13, 2014Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
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Patent number: 8852922Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.Type: GrantFiled: August 30, 2011Date of Patent: October 7, 2014Assignee: Meso Scale Technologies, LLCInventors: Eli N. Glezer, Jonathan K. Leland, Mark A. Billadeau, Joseph M. Leginus, Bandele Jeffrey-Coker, Jeff D. Debad, Koustubh A. Phalnikar, Sriram Jambunathan
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Publication number: 20140274805Abstract: Materials and Methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.Type: ApplicationFiled: April 10, 2014Publication date: September 18, 2014Applicant: MESO SCALE TECHNOLOGIES LLCInventors: Jacob N. WOHLSTADTER, James L. WILBUR, George B. SIGAL, Mark T. MARTIN, Liang-Hong GUO, Alan FISCHER, Jon LELAND, Mark A. BILLADEAU, Larry R. HELMS, Ramin DARVARI