Abstract: Provided herein are compositions, systems, and methods for causing weight loss and treating and/or preventing a disease or condition, such as obesity, diabetes, and cancer, with an agent or procedure that inhibits the TMA/FMO3/TMAO pathway in a subject.

Abstract: A smartphone and app executed on the smartphone are used for personal pathogen status verifying that allows an entity to control access to an area of congregation (AOC) at one or more points of entry (POE). In one embodiment, the system may be used for the SARS-CoV-2 virus, but may be similarly used for other pathogens.

Abstract: Virtual assistants intelligently emulate a representative of a service provider by providing variable responses to user queries received via the virtual assistants. These variable responses may take the context of a user's query into account both when identifying an intent of a user's query and when identifying an appropriate response to the user's query.

Abstract: A method is provided of configuring a field device for monitoring and/or controlling an operation(s) of a process or plant. The method includes conducting web-based communication between a networked computer device and the field device over an Ethernet-APL to allow the networked computer device to access and interact with a web page(s) or program(s) that is hosted on a web server running on the field device. The method also includes configuring at the field device an operation parameter(s) and/or setting(s) of the field device based on user input received across the Ethernet-APL by the field device from user interaction with the web page(s) or program(s) through the networked computer device.

Abstract: Described are examples for providing end-to-end intent definition of network functions for network slice management. Intents are defined for each level of network constituent including slices, slice subnets, and management functions. A system of intent based network slice management includes a network slice management function (NSMF) configured to receive a service profile from a communication service management function (CSMF) and derive an intent for each desired network slice subnet for a network slice subnet management function (NSSMF). The NSSMF is configured to derive requirements for a plurality of network functions (NFs) and provide an intent defining the requirements of a respective NF to a network function management function (NFMF). The NFMF is configured to receive the intent for the respective NF via an intent-based interface for management of NFs and derive a network resource model (NRM) for the respective NF based on the intent.

Abstract: Techniques for adjusting the strengths of signals received from a transmitter based on the transmitter's likely location are disclosed herein. An example method includes receiving, by one or more processors, location information corresponding to one or more respective areas expected to be visited by an individual; receiving, by the one or more processors, measurements indicative of signal strengths of one or more signals transmitted by a transmitter associated with the individual and received by one or more receivers configured to receive one or more signals transmitted by the transmitter, the one or more receivers being positioned at respective receiver locations corresponding to one or more respective areas; and adjusting, by the one or more processors, the received measurements indicative of the signal strengths of the one or more signals transmitted by the transmitter based on the one or more respective areas expected to be visited by the individual.

Abstract: Techniques for adjusting the sizes of geo-fences based on an individual's likely location are disclosed herein. An example method includes determining one or more geo-fenced zones corresponding to one or more respective areas; receiving location information indicative of the one or more areas expected to be visited by the individual, of the one or more respective areas; and adjusting the one or more geo-fenced zones based on the one or more respective areas expected to be visited by the individual.

Abstract: Systems and methods for rendering spatial audio in accordance with embodiments of the invention are illustrated. One embodiment includes a spatial audio system, including a primary network connected speaker, including a plurality of sets of drivers, where each set of drivers is oriented in a different direction, a processor system, memory containing an audio player application, wherein the audio player application configures the processor system to obtain an audio source stream from an audio source via the network interface, spatially encode the audio source, decode the spatially encoded audio source to obtain driver inputs for the individual drivers in the plurality of sets of drivers, where the driver inputs cause the drivers to generate directional audio.

Abstract: Described are examples for providing intent based network slice management using a management data analytics function (MDAF) to predict deficiencies. A network management system receives an intent for a network slice constituent. The network management system configures computing resources for the network slice constituent to satisfy the intent based on expected performance of the computing resources. The network management system receives feedback with respect to actual performance of the network slice constituent. The network management system determines, based on analysis of the feedback by a management data analytics function (MDAF), a predicted deficiency of the network slice constituent not being able to satisfy the intent. The network management system modifies the configuration of the computing resources based on the feedback and the predicted deficiency to satisfy the intent.

Abstract: The present invention is directed to compositions comprising an extrudate or solid solution of a compound, or a salt thereof, of Formula I (API): wherein “Ra” is independently —H or —F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made therefrom to rapidly disintegrate in the environment in which the API is to be released.

Abstract: A label modification unit may receive a label modification input that indicates a label modification associated with content being written to a label or erased from the label. The label modification unit may identify an area of the label that is associated with the label modification according to the label modification input. The label modification unit may determine, based on a size of the area, a spot size of a light beam that is configured to be emitted by a laser printhead to modify the content within the area. The label modification unit may determine, based on the spot size and the content, an optical path configuration for the laser printhead. The label modification unit may operate the laser printhead according to the optical path configuration to write the content to the area or erase the content from the area.

Abstract: Disclosed herein are various methods and apparatus for performing charge detection mass spectrometry (CDMS). In particular, techniques are disclosed for monitoring a detector signal from a CDMS device to determine how many ions are present in the ion trap (10) of the CDMS device. For example, if no ions are present the measurement can then be terminated early. Similarly, if more than one ion is present, the measurement can be terminated early, or ions can be removed from the trap (10) until only a single ion remains. Techniques are also provided for increasing the probability of there being a single ion in the trap (10). A technique for attenuating an ion beam is also provided.

Abstract: Examples can include a system for video chat cycles within a social media application. An organizer platform can be used to design a schedule for the video chat cycles. This can include scheduled organizer content before, after, and between video chats. The organizer content can include graphics, video, and even live streams by the organizer.

Abstract: A rodent-proof barrier material comprising a settable carrier medium and a plurality of filaments dispersed within the settable carrier medium. Each filament of the plurality of filaments comprises a central curved portion and first and second end portions.

Abstract: Disclosed herein are various methods and apparatus for performing charge detection mass spectrometry (CDMS). In particular, techniques are disclosed for monitoring a detector signal from a CDMS device to determine how many ions are present in the ion trap (10) of the CDMS device. For example, if no ions are present the measurement can then be terminated early. Similarly, if more than one ion is present, the measurement can be terminated early, or ions can be removed from the trap (10) until only a single ion remains. Techniques are also provided for increasing the probability of there being a single ion in the trap (10). A technique for attenuating an ion beam is also provided.

Abstract: An expansion joint for providing a rodent-proof barrier. The expansion joint comprises an elongate core formed of a resiliently deformable material, and a flexible sheath of a barrier material covering at least a part of the elongate portion of the elongate core. The elongate portion of the elongate core is compressible in a direction perpendicular to a line between the first and second ends of the elongate core, the elongate core being arranged to be compressed and inserted into a gap between first and second building structures, and to expand after insertion into the gap so that the expansion joint is held in place within the gap by friction between the surface of the flexible sheath and the surfaces of the first and second building structures.

Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-672 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitopes: PHATFKAMA YKEGTM (42-56) and YQCVQGYRALH (150-160) on CD25. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.

Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-634 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.

Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.

Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.