Patents by Inventor Mark A. Bush

Mark A. Bush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160022781
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: July 30, 2015
    Publication date: January 28, 2016
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20140228288
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 14, 2014
    Applicant: GlaxoSmithKline, LLC
    Inventors: Mark A. BUSH, Murray W. Stewart, Yonghong Yang
  • Publication number: 20140228284
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 14, 2014
    Applicant: GlaxoSmithKline, LLC
    Inventors: Mark A. BUSH, Murray W. Stewart, Yonghong Yang
  • Patent number: 8748377
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: June 10, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Mark A. Bush, Murray W. Stewart, Yonghong Yang
  • Publication number: 20140066371
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: July 19, 2013
    Publication date: March 6, 2014
    Applicant: GlaxoSmithKline
    Inventors: Mark A. BUSH, Jessica E. MATTHEWS, Susan E. WALKER
  • Publication number: 20130231282
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: May 4, 2012
    Publication date: September 5, 2013
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20130225489
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: May 4, 2012
    Publication date: August 29, 2013
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20130005652
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: June 12, 2012
    Publication date: January 3, 2013
    Inventors: Mark A. BUSH, Jcssica E. Matthews, Susan E. Walker
  • Patent number: 8338369
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: December 25, 2012
    Assignee: Glaxosmithkline LLC
    Inventors: Mark A. Bush, Jessica E. Matthews, Susan E. Walker
  • Patent number: 8202837
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: June 19, 2012
    Assignee: GlaxoSmithKline LLC
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20110301080
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: December 10, 2009
    Publication date: December 8, 2011
    Inventors: Mark A. Bush, Murray W. Stewart, Yonghong Yang
  • Publication number: 20100009910
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: September 12, 2007
    Publication date: January 14, 2010
    Inventors: Mark A. Bush, Jessica E. Matthews, Susan E. Walker
  • Publication number: 20080254087
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: November 3, 2006
    Publication date: October 16, 2008
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Patent number: 4818413
    Abstract: The copper corrosion rate is minimized to a certain discharge limit by providing a chlorine-bromide treatment in which the chemical feed rate of bromide is increased to an amount required to decrease the copper corrosion rate to the rate required to meet the discharge limit. The inventors made the unexpected and surprising discovery that an increase in the chemical feed rate of bromide--even when the chlorine feed rate is constant--has the effect of reducing copper corrosion. Therefore, this effect is useful for adjusting the copper corrosion rate to an optimum rate to most economically achieve a certain discharge limit.
    Type: Grant
    Filed: August 5, 1987
    Date of Patent: April 4, 1989
    Assignee: Nalco Chemical Company
    Inventors: Richard L. Hoover, Mark A. Bush