Patents by Inventor Mark A. Bush

Mark A. Bush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160022781
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: July 30, 2015
    Publication date: January 28, 2016
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20140228288
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 14, 2014
    Applicant: GlaxoSmithKline, LLC
    Inventors: Mark A. BUSH, Murray W. Stewart, Yonghong Yang
  • Publication number: 20140228284
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 14, 2014
    Applicant: GlaxoSmithKline, LLC
    Inventors: Mark A. BUSH, Murray W. Stewart, Yonghong Yang
  • Patent number: 8748377
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: June 10, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Mark A. Bush, Murray W. Stewart, Yonghong Yang
  • Publication number: 20140066371
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: July 19, 2013
    Publication date: March 6, 2014
    Applicant: GlaxoSmithKline
    Inventors: Mark A. BUSH, Jessica E. MATTHEWS, Susan E. WALKER
  • Publication number: 20130231282
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: May 4, 2012
    Publication date: September 5, 2013
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20130225489
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: May 4, 2012
    Publication date: August 29, 2013
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20130005652
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: June 12, 2012
    Publication date: January 3, 2013
    Inventors: Mark A. BUSH, Jcssica E. Matthews, Susan E. Walker
  • Patent number: 8338369
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: December 25, 2012
    Assignee: Glaxosmithkline LLC
    Inventors: Mark A. Bush, Jessica E. Matthews, Susan E. Walker
  • Patent number: 8202837
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: June 19, 2012
    Assignee: GlaxoSmithKline LLC
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20110301080
    Abstract: The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
    Type: Application
    Filed: December 10, 2009
    Publication date: December 8, 2011
    Inventors: Mark A. Bush, Murray W. Stewart, Yonghong Yang
  • Patent number: 7848093
    Abstract: Portable devices configured to be worn as a belt buckle are disclosed herein. The portable device includes a housing, a first connector attached to the housing and adapted to slideably receive a belt, and a second connector attached to the housing and adapted to secure the housing to the belt.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: December 7, 2010
    Inventors: Winston B. Hardson, Mark Bush
  • Publication number: 20100009910
    Abstract: The present invention relates to methods and pharmaceutical compositions relating to administering hypoglycemic agents and/or GLP-1 agonists wherein the mean maximum plasma concentration (Cmax) and/or Area Under the Curve (AUC) values of the hypoglycemic agent are increased and/or sustained.
    Type: Application
    Filed: September 12, 2007
    Publication date: January 14, 2010
    Inventors: Mark A. Bush, Jessica E. Matthews, Susan E. Walker
  • Publication number: 20080254087
    Abstract: The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.
    Type: Application
    Filed: November 3, 2006
    Publication date: October 16, 2008
    Inventors: Mark A. Bush, Mary Colleen O'Neill
  • Publication number: 20080024976
    Abstract: Portable devices configured to be worn as a belt buckle are disclosed herein. The portable device includes a housing, a first connector attached to the housing and adapted to slideably receive a belt, and a second connector attached to the housing and adapted to secure the housing to the belt.
    Type: Application
    Filed: February 6, 2007
    Publication date: January 31, 2008
    Inventors: Winston Hardson, Mark Bush
  • Publication number: 20070131711
    Abstract: A bag-in-box type of assembly is disclosed where numerous features are provided. One of the features helps to lock the drainage tube of the bag in a predetermined position at the bottom of the box. Another feature is directed to a ramp inside the box that aid drainage of the bag's content, e.g., concentrate for a postmix beverage. Yet a further feature is directed to structures that prevent slippage of the bag when placed on the ramp.
    Type: Application
    Filed: March 31, 2006
    Publication date: June 14, 2007
    Applicant: Carrier Corporation
    Inventors: James Minard, Mark Bush
  • Publication number: 20070131715
    Abstract: A beverage dispenser provides numerous inventive features in its refrigeration system, diluent delivery system, concentrate delivery system, mixing and dispensing system, and control system. For example, the mixing and dispensing system includes a mixing nozzle that has several novel aspects. Such novel aspects include an elevated blocking surface that directly faces the inlet of a pressurized diluent in order to create turbulence for the mixing, and novel constructions of a depressurizing section together with a funnel-shaped passageway that reduces splashing.
    Type: Application
    Filed: March 31, 2006
    Publication date: June 14, 2007
    Applicant: Carrier Corporation
    Inventors: James Minard, Mark Bush, Peter McNamee
  • Publication number: 20060204390
    Abstract: Mix and air combine in a mixing chamber of a housing of a frozen product system to form a mixture. A cap received in one end of the housing includes an air inlet, a mix inlet, and two mixture outlets. An integral orifice received in the air inlet regulates the amount of air that flows into the mixing chamber. A gasket positioned adjacent the cap provides a liquid tight seal that prevents air and mix from entering the mixing chamber when the mixture is dispensed from the mixing chamber and to prevent the mixture from exiting the freezing cylinder while air and mix are drawn into the mixing chamber. The gasket includes an air valve, a mix valve, and two mixture valves. An adapter draws air into the pump through an air hole and draws mix into the pump through a mix hole. A piston slides in the mixing chamber to dispense the mixture through mixture holes. The cap includes a plurality of protrusions that engage holes in the adapter to ensure proper alignment of the cap and the adapter.
    Type: Application
    Filed: May 15, 2006
    Publication date: September 14, 2006
    Inventors: Mark Bush, Pete McNamee, James Minard
  • Patent number: 7048523
    Abstract: Mix and air combine in a mixing chamber of a housing of a frozen product system to form a mixture. A cap received in one end of the housing includes an air inlet, a mix inlet, and two mixture outlets. An integral orifice received in the air inlet regulates the amount of air that flows into the mixing chamber. A gasket positioned adjacent the cap provides a liquid tight seal that prevents air and mix from entering the mixing chamber when the mixture is dispensed from the mixing chamber and to prevent the mixture from exiting the freezing cylinder while air and mix are drawn into the mixing chamber. The gasket includes an air valve, a mix valve, and two mixture valves. An adapter draws air into the pump through an air hole and draws mix into the pump through a mix hole. A piston slides in the mixing chamber to dispense the mixture through mixture holes. The cap includes a plurality of protrusions that engage holes in the adapter to ensure proper alignment of the cap and the adapter.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: May 23, 2006
    Assignee: Carrier Commercial Refrigeration, Inc.
    Inventors: Mark Bush, Pete McNamee, James J. Minard
  • Patent number: 7014076
    Abstract: A syrup delivery system delivers flavored syrup. A solenoid introduces air into the system and into an inlet of an exhaust diverter including a flexible diaphragm. The air exits the exhaust diverter through an outlet for entry into a syrup valve that dispenses the syrup. After dispensing of the syrup, the solenoid blocks air from entering the system. The air from the syrup valve reenters the exhaust diverter through the outlet. The air exits the exhaust diverter through the contaminated air exhaust. The air pushes on the flexible diaphragm, which contacts a seating surface around the inlet, preventing the air from exiting the exhaust diverter through the inlet. The remaining air in the system passes into the expansion tank and is diffused, causing any contaminates in the air to fall to the bottom of the expansion tank. The exhaust air is also subjected to a turbulent air flow path in the expansion tank that further separate any contaminants from the air.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: March 21, 2006
    Assignee: Carrier Commercial Registration, Inc.
    Inventors: James J. Minard, Pete McNamee, Mark Bush, Jon Peter Gilchrist