Patents by Inventor Mark A. Cole

Mark A. Cole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240358272
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Application
    Filed: March 15, 2024
    Publication date: October 31, 2024
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 11963753
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: April 23, 2024
    Assignee: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 11130004
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: September 28, 2021
    Assignee: Cianna Medical, Inc.
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20210204832
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Application
    Filed: November 16, 2020
    Publication date: July 8, 2021
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 10835150
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: November 17, 2020
    Assignee: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 10201716
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: February 12, 2019
    Assignee: CIANNA MEDICAL, INC.
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20190022410
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Application
    Filed: July 30, 2018
    Publication date: January 24, 2019
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Patent number: 9470408
    Abstract: An illumination system may include a receiver which is mounted on a support surface, such as a heat sink, and a light module that may include a cover and an LED assembly. The LED assembly is rotateably attached to the cover and seats within the receiver. The receiver may have touch-safe terminals attached thereto for providing power to the LED assembly. The LED assembly may include a cup which enables potting material to be easily included in the assembly during manufacturing. When the LED assembly is attached to the receiver, blades on the LED assembly mate with the terminals on the receiver.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: October 18, 2016
    Assignee: Molex, LLC
    Inventors: Daniel B. McGowan, Victor Zaderej, Mark A. Cole
  • Patent number: 8892185
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: November 18, 2014
    Assignee: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 8858415
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: October 14, 2014
    Assignee: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, George D. Hermann, Mark A. Cole, Mark A. Richart, Than Nguyen, Gail S. Lebovic
  • Publication number: 20140063814
    Abstract: An illumination system may include a receiver which is mounted on a support surface, such as a heat sink, and a light module that may include a cover and an LED assembly. The LED assembly is rotateably attached to the cover and seats within the receiver. The receiver may have touch-safe terminals attached thereto for providing power to the LED assembly. The LED assembly may include a cup which enables potting material to be easily included in the assembly during manufacturing. When the LED assembly is attached to the receiver, blades on the LED assembly mate with the terminals on the receiver.
    Type: Application
    Filed: April 24, 2012
    Publication date: March 6, 2014
    Applicant: Molex Incorporated
    Inventors: Daniel B. McGowan, Victor Zaderej, Mark A. Cole
  • Publication number: 20140066754
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Application
    Filed: November 13, 2013
    Publication date: March 6, 2014
    Applicant: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Publication number: 20110137103
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Application
    Filed: December 30, 2010
    Publication date: June 9, 2011
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20110021888
    Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.
    Type: Application
    Filed: June 25, 2010
    Publication date: January 27, 2011
    Applicant: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, Mark A. Cole, Tommy G. Nguyen
  • Patent number: 7862496
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: January 4, 2011
    Assignee: Cianna Medical, Inc.
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20100204537
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Application
    Filed: April 21, 2010
    Publication date: August 12, 2010
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Patent number: 7574928
    Abstract: An air particle sample cassette enables concurrent or sequential collection of air particle samples. The dual air particle sample cassette has top and bottom covers that fit together to provide an airtight seal between them. The airtight seal may be provided by adhesive or otherwise. However, a close fit between the two also aids in obtaining an airtight seal. The top cover has tapering inlets circumscribed by channels. The inlets taper to create increased air speed at the exit slit of the inlets. The inlets have rounded tops for greater collection of air and the circumscribing channels provide means by which plastic caps or otherwise may be used to protect the inlets from collecting air until desired. The sample plate or collecting slide is fitted to the bottom of the top cover and obstructs the direct flow of air to the exit port. The collecting slide is protected from contact with other cassette elements by spacers or sidewalls which generally leave the corners of the bottom cover open.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: August 18, 2009
    Assignee: Innovative Sampling Solutions, Inc.
    Inventors: Mark A. Cole, Thomas J. Johnston
  • Patent number: 7306813
    Abstract: The present invention describes a means for fixing skin care ingredients on the surface of non-woven webs and cellulosic mats. The active ingredients can be released (deposited) onto the skin by normal triggering mechanisms, which include the action of water or urine or by friction or rubbing. The fixative systems described herein provide the ability to control high load levels while not interfering with the wettabliity of the fabric or paper. Additionally, incompatible/reactive ingredients can be treated onto the same web and are kept as separate particles fixed to the surface until released.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: December 11, 2007
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: James L. Eden, Mark A. Cole, Remo Santacecilia
  • Patent number: 7155988
    Abstract: An air particle sample cassette enables concurrent or sequential collection of air particle samples. The dual air particle sample cassette has top and bottom covers that fit together to provide an airtight seal between them. The airtight seal may be provided by adhesive or otherwise. However, a close fit between the two also aids in obtaining an airtight seal. The top cover has tapering inlets circumscribed by channels. The inlets taper to create increased air speed at the exit slit of the inlets. The inlets have rounded tops for greater collection of air and the circumscribing channels provide means by which plastic caps or otherwise may be used to protect the inlets from collecting air until desired. The sample plate or collecting slide is fitted to the bottom of the top cover and obstructs the direct flow of air to the exit port. The collecting slide is protected from contact with other cassette elements by spacers or sidewalls which generally leave the corners of the bottom cover open.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: January 2, 2007
    Assignee: Innovative Sampling Solutions, Inc.
    Inventors: Mark A. Cole, Thomas J. Johnston
  • Patent number: 7141108
    Abstract: The present invention describes a means for fixing skin care ingredients on the surface of non-woven webs and cellulosic mats. The active ingredients can be released (deposited) onto the skin by normal triggering mechanisms, which include the action of water or urine or by friction or rubbing. The fixative systems described herein provide the ability to control high load levels while not interfering with the wettabliity of the fabric or paper. Additionally, incompatible/reactive ingredients can be treated onto the same web and are kept as separate particles fixed to the surface until released.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: November 28, 2006
    Assignee: National Starch and Chemical Investment Holding Corp.
    Inventors: James L. Eden, Mark A. Cole, Remo Santacecilia