Abstract: A method of estimating the probability of a seizure in a subject, the method comprising: receiving historical data associated with epileptic events experienced by the subject over a first time period, the historical data comprising physiological data associated with each epileptic event and a time at which each epileptic event occurred; generating a temporal probability model of future epileptic events based on the time of each of the epileptic events, the temporal probability model representing a probability of a future seizure occurrence in each of a plurality of time windows; generating a probabilistic model based on the physiological data associated with each epileptic event; weighting the probabilistic model based on the temporal probability model to generate a weighted probabilistic model of future seizure activity; and outputting an estimate of seizure probability in the subject using the weighted probabilistic model.

Abstract: A method of estimating the probability of a seizure in a subject, the method comprising: receiving historical data associated with epileptic events experienced by the subject over a first time period, the historical data comprising physiological data associated with each epileptic event and a time at which each epileptic event occurred; generating a temporal probability model of future epileptic events based on the time of each of the epileptic events, the temporal probability model representing a probability of a future seizure occurrence in each of a plurality of time windows; generating a probabilistic model based on the physiological data associated with each epileptic event; weighting the probabilistic model based on the temporal probability model to generate a weighted probabilistic model of future seizure activity; and outputting an estimate of seizure probability in the subject using the weighted probabilistic model.

Abstract: A method of estimating the probability of a seizure in a subject, the method comprising: receiving historical data associated with epileptic events experienced by the subject over a first time period, the historical data comprising physiological data associated with each epileptic event and a time at which each epileptic event occurred; generating a temporal probability model of future epileptic events based on the time of each of the epileptic events, the temporal probability model representing a probability of a future seizure occurrence in each of a plurality of time windows; generating a probabilistic model based on the physiological data associated with each epileptic event; weighting the probabilistic model based on the temporal probability model to generate a weighted probabilistic model of future seizure activity; and outputting an estimate of seizure probability in the subject using the weighted probabilistic model.

Abstract: A trailer 10 includes a frame 12 having a central axis 14 spaced between rear wheels. A plurality of storage units 20 are supported on the trailer frame, with each storage unit supporting a plurality of objects thereon. Each storage support has a support axis 22 substantially parallel to the frame central axis. A carriage assembly 24 rotates the plurality of storage supports, and a lift mechanism 30 raises and lowers the carriage assembly.

Abstract: It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-intestinal alkaline phosphatase antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

Abstract: An actuator is configured for transmitting a force or torque to a load. In one example configuration, the actuator includes an input device configured to apply an output force. A backstopping clutch is configured to transmit torque only in the input direction and to prevent back-driving of the input device. An overrunning clutch is configured to include a driven member moved in response to the transmitted torque in the input direction. The load may be moved in response to the driven member, or the load may be moved by a force applied directly to the load.

Abstract: A method for reducing phosphate absorption in a human or non-human animal subject at risk of developing or having developed hyperphosphatemia is disclosed. The method includes the step of administering orally to the subject an anti-intestinal sodium phosphate cotransporter type 2B (Npt2B) antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

Abstract: A protective gear socket assembly includes a gear socket and an insert positioned in the gear socket. The gear socket includes a plurality of teeth projecting radially outward from a perimeter of the gear socket and a u-shaped channel formed through a thickness of the gear socket, a contact surface extending radially outward from an upper edge of the u-shaped channel of the gear socket, and at least one mounting hole formed in the contact surface. The insert includes a u-shaped channel formed through a thickness of the insert, a mating surface extending radially outward from a lower edge of the u-shaped channel of the insert, and at least one mounting post extending from the mating surface.

Abstract: A protective gear socket assembly includes a gear socket and an insert positioned in the gear socket. The gear socket includes a plurality of teeth projecting radially outward from a perimeter of the gear socket and a u-shaped channel formed through a thickness of the gear socket, a contact surface extending radially outward from an upper edge of the u-shaped channel of the gear socket, and at least one mounting hole formed in the contact surface. The insert includes a u-shaped channel formed through a thickness of the insert, a mating surface extending radially outward from a lower edge of the u-shaped channel of the insert, and at least one mounting post extending from the mating surface.

Abstract: A trailer (10) or container (11) includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carousel (24) rotates the plurality of storage supports, and a powered drive rotates the carousel. The system includes a storage location signal, a vehicle location signal, and a door closed signal which are each input to a controller (90) for controlling rotation of the carousel, so that goods to be unloaded are on a support which is rotated to an unloading position.

Abstract: A precision garden hoe includes a blade having a curved upper edge, a curved lower edge, pointed tips at the sides where the edges meet, and front and rear surfaces; a handle adapted to be held by a user; and a shaft having a front end attached to the rear surface of the blade, a rear end attached to the handle, and a bend so that the blade is at a non-perpendicular angle relative to the handle. The edges of the blade may be sharp. The bend in the shaft may be at an angle so that, when attached at a perpendicular angle to the front end of the shaft, the blade will be at a non-perpendicular angle relative to the rear end of the shaft.

Abstract: A trailer 10 includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carousel assembly (24) rotates the plurality of storage supports, and may be raised and lowered. A locking mechanism (180) is provided for engaging the carousel to prevent the carousel from inadvertently moving to the lowered position. A tire support mechanism (210) includes an elongate restraint engaging an upright tire when a ratchet mechanism renders a flexible member taut.

Abstract: Methods for increasing antigen-specific egg yolk antibody titer and eggs having increased antigen-specific egg yolk antibody titer are disclosed. More specifically, the method for increasing antibody titer may include the steps of: administering to an egg-laying animal a corticosteroid; and then, exposing the animal to an immunogenic dose of the antigen.

Abstract: A trailer (10) or container (11) includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carousel (24) rotates the plurality of storage supports, and a powered drive rotates the carousel. The system includes a storage location signal, a vehicle location signal, and a door closed signal which are each input to a controller (90) for controlling rotation of the carousel, so that goods to be unloaded are on a support which is rotated to an unloading position.

Abstract: It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-intestinal alkaline phosphatase antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

Abstract: A method for reducing phosphate absorption in a human or non-human animal subject at risk of developing or having developed hyperphosphatemia is disclosed. The method includes the step of administering orally to the subject an anti-intestinal sodium phosphate cotransporter type 2B (Npt2B) antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

Abstract: It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-phytic acid (C6H6[OPO(OH)2]o) antibody or an anti-phytate antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

Abstract: A trailer 10 includes a frame 12 having a central axis 14 spaced between rear wheels. A plurality of storage units 20 are supported on the trailer frame, with each storage unit supporting a plurality of objects thereon. Each storage support has a support axis 22 substantially parallel to the frame central axis. A carriage assembly 24 rotates the plurality of storage supports, and a lift mechanism 30 raises and lowers the carriage assembly.

Abstract: A trailer 10 includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports or bins (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carriage assembly (24) rotates the plurality of storage supports. A powered drive (110) rotates the carriage assembly, and a powered brake (112) prohibits rotation of the carriage assembly when power is not applied to the motor. During rotation of the storage supports, a lower portion of a storage support rotates below the rear wheel axis.