Patents by Inventor Mark A. Dexter
Mark A. Dexter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240102132Abstract: A metal matrix composite to high tolerate wear as a property has been produced by infiltration casting of a Fe Alloy and a spinel ceramic by using a material design for i) metal transport phenomena conditions, ii) predefined wetting and capillarity and iii) processing child insert/mother casting methodology to produce a final casting in shape and form to meet the needs of a mining end user.Type: ApplicationFiled: December 3, 2021Publication date: March 28, 2024Applicant: ME Global Inc.Inventors: Aaron James Garland, Joaquin Aguilar Santillan, Antony Pieter, Shayne Allen Berns, Mark Dexter Hines, Ricardo Rodrigo Leiva lllanes, Benjamin Zimmerman, Daniel William Ruffelle
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Patent number: 9988431Abstract: The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.Type: GrantFiled: March 21, 2013Date of Patent: June 5, 2018Assignee: The Walter and Eliza Hall Institute of Medical ResearchInventors: Mireille Hanna Lahoud, Anna Irene Proietto, Irina Caminschi, Ken Shortman, Andrew Mark Lew, Li Wu, Mark Dexter Wright
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Publication number: 20150265721Abstract: The present invention relates to the identification of proteins which bind the dendritic cell marker known as Clec9A. The present invention provides new compounds for targeting therapeutic agents such as antigens to dendritic cells. Also provided are methods of modulating a humoral and/or T cell mediated immune response to the antigen, methods of delivery of a cytotoxic agent to dendritic cells thereof involved in diseased states, methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, and methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.Type: ApplicationFiled: December 23, 2014Publication date: September 24, 2015Inventors: Mireille Hanna Lahoud, Irina Caminschi, Ken Shortman, Jian-Guo Zhang, Mark Francis Van Delft, David Ching Siang Huang, Nicos Anthony Nicola, Alan Frederick Cowman, Mark Dexter Wright
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Publication number: 20140335104Abstract: The present invention relates to methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, which can be used to treat and/or prevent diseases such as cancer, autoimmunity and infections. The present invention also relates to methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof. The present invention further relates to methods of detecting cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.Type: ApplicationFiled: April 14, 2014Publication date: November 13, 2014Inventors: Mireille Hanna Lahoud, Irina Caminschi, Ken Shortman, Jian-Guo Zhang, Mark Francis Van Delft, David Ching Siang Huang, Mark Dexter Wright
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Patent number: 8649211Abstract: An integrated circuit containing a memory array with memory bits and a differential sense amplifier for reading the logic state of the memory bits. The integrated circuit also contains redundant vias which are in the via path that couples a bitline to Vss. Moreover, an integrated circuit containing a FLASH memory bit with redundant vias in the via path from the bitline to Vss.Type: GrantFiled: June 20, 2012Date of Patent: February 11, 2014Assignee: Texas Instruments IncorporatedInventors: Mark A. Dexter, Sarma S. Gunturi
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Publication number: 20130273150Abstract: The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.Type: ApplicationFiled: March 21, 2013Publication date: October 17, 2013Inventors: Mireille Hanna Lahoud, Anna Irene Proietto, Irina Caminschi, Ken Shortman, Andrew Mark Lew, Li Wu, Mark Dexter Wright
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Patent number: 8426565Abstract: The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.Type: GrantFiled: August 29, 2008Date of Patent: April 23, 2013Assignee: Walter and Eliza Hall Institute of Medical ResearchInventors: Mireille Hanna Lahoud, Anna Irene Proietto, Irina Caminschi, Ken Shortman, Andrew Mark Lew, Li Wu, Mark Dexter Wright
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Patent number: 8379447Abstract: An integrated circuit containing a memory array with memory bits and a differential sense amplifier for reading the logic state of the memory bits. The integrated circuit also contains redundant vias which are in the via path that couples a bitline to Vss. Moreover, an integrated circuit containing a FLASH memory bit with redundant vias in the via path from the bitline to Vss.Type: GrantFiled: June 30, 2010Date of Patent: February 19, 2013Assignee: Texas Instruments IncorporatedInventors: Mark A. Dexter, Sarma S. Gunturi
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Publication number: 20120257441Abstract: An integrated circuit containing a memory array with memory bits and a differential sense amplifier for reading the logic state of the memory bits. The integrated circuit also contains redundant vias which are in the via path that couples a bitline to Vss. Moreover, an integrated circuit containing a FLASH memory bit with redundant vias in the via path from the bitline to Vss.Type: ApplicationFiled: June 20, 2012Publication date: October 11, 2012Applicant: Texas Instruments IncorporatedInventors: Mark A. Dexter, Sarma S. Gunturi
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Publication number: 20120039806Abstract: The present invention relates to the identification of proteins which bind the dendritic cell marker known as Clec9A. The present invention provides new compounds for targeting therapeutic agents such as antigens to dendritic cells. Also provided are methods of modulating a humoral and/or T cell mediated immune response to the antigen, methods of delivery of a cytotoxic agent to dendritic cells thereof involved in diseased states, methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, and methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.Type: ApplicationFiled: March 22, 2010Publication date: February 16, 2012Inventors: Mireille Hanna Lahoud, Irina Caminschi, Jian-Guo Zhang, Mark Francis Van Delft, David Ching Siang Huang, Nicos Anthony NIcola, Alan Cowman, Mark Dexter Wright
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Publication number: 20120002471Abstract: An integrated circuit containing a memory array with memory bits and a differential sense amplifier for reading the logic state of the memory bits. The integrated circuit also contains redundant vias which are in the via path that couples a bitline to Vss. Moreover, an integrated circuit containing a FLASH memory bit with redundant vias in the via path from the bitline to Vss.Type: ApplicationFiled: June 30, 2010Publication date: January 5, 2012Applicant: TEXAS INSTRUMENTS INCORPORATEDInventors: Mark A. Dexter, Sarma S. Gunturi
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Publication number: 20110126301Abstract: The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.Type: ApplicationFiled: August 29, 2008Publication date: May 26, 2011Inventors: Mireille Hanna Lahoud, Anna Irene Proietto, Irina Caminschi, Ken Shortman, Andrew Mark Lew, Li Wu, Mark Dexter Wright
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Publication number: 20110110861Abstract: The present invention relates to methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, which can be used to treat and/or prevent diseases such as cancer, autoimmunity and infections. The present invention also relates to methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof. The present invention further relates to methods of detecting cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.Type: ApplicationFiled: May 1, 2009Publication date: May 12, 2011Inventors: Mireille Hanna Lahoud, Irina Caminschi, Ken Shortman, Jian-Guo Zhang, Mark Francis Van Delft, David Ching Siang Huang, Mark Dexter Wright
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Publication number: 20080247508Abstract: A device used to warm a mammography machine comprises a warmer and a holder for the warmer. The holder includes an enclosed heating element and non-insulating filler material adjacent the heating element. The heating element is precisely regulated to ensure that the sensitive imaging elements are not damaged by an overtemperature condition, while at the same time permitting a rapid heating of the warmer for high cycle use. The warmer warms surfaces of the mammography machine that contacts human skin.Type: ApplicationFiled: October 13, 2006Publication date: October 9, 2008Inventors: Ann Harrington, Mark Dexter, William Pedersen