Patents by Inventor Mark A. Freyberg

Mark A. Freyberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTANCE FOR THE TREATMENT OF INFECTIONS
    Publication number: 20150250820
    Abstract: The invention relates to the use of dichloric acids and the derivatives thereof for producing medicaments used for disinfecting body cavities.
    Type: Application
    Filed: October 7, 2014
    Publication date: September 10, 2015
    Inventors: Dirk Kaiser, Mark A. Freyberg
  • Apoptotically active peptides
    Patent number: 9017693
    Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: April 28, 2015
    Assignee: Cytotools AG
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Method for Treating Arteriosclerosis
    Publication number: 20120282277
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Application
    Filed: July 13, 2012
    Publication date: November 8, 2012
    Applicant: CYTOTOOLS AG
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Method for treating vascular disorders
    Patent number: 8252283
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: August 28, 2012
    Assignee: Cytotools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Apoptotically Active Peptides
    Publication number: 20110178000
    Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
    Type: Application
    Filed: December 23, 2010
    Publication date: July 21, 2011
    Applicant: CYTOTOOLS AG
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Apoptotically active peptides
    Patent number: 7892556
    Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: February 22, 2011
    Assignee: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Agents, Which Inhibit Apoptosis in Cells that are Involved in Wound Healing
    Publication number: 20100111931
    Abstract: The invention relates to the use of substances as a fundamental constituent in wound healing agents. The invention is characterized in that said substances bond to either IAP and/or integrin ?v?3 and/or thrombospondin-1 in such a way that the bond between thrombospondin-1 and IAP and/or integrin ?v?3 is inhibited.
    Type: Application
    Filed: August 28, 2009
    Publication date: May 6, 2010
    Applicant: DERMATOOLS BIOTECH GMBH
    Inventors: Mark Freyberg, Peter Friedl, Dirk Kaiser
  • Anti-apoptotically active apatamers
    Patent number: 7655773
    Abstract: The invention relates to anti-apoptotically active apatamers. The invention describes possible therapeutic and diagnostic applications for, among other things, treating arteriosclerosis, promoting the healing of wounds, treating AIDS, cancer, Alzheimer's disease, systemic lupus erythematosus as well a rheumatoid arthritis and other chronic inflammatory diseases.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: February 2, 2010
    Assignee: CytoTools AG
    Inventors: Gerd Klock, Mark A. Freyberg, Dirk Kaiser
  • Agents, which inhibit apoptosis in cells that are involved in wound healing
    Patent number: 7582725
    Abstract: The invention relates to the use of substances as a fundamental constituent in wound healing agents. The invention is characterised in that said substances bond to either IAP and/or integrin ?v?3 and/or thrombuspondin-1 in such a way that the bond between thrumbospondin-1 and IAP and/or integrin ?v?3 is inhibited.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: September 1, 2009
    Assignee: Dermatools Biotech GmbH
    Inventors: Mark Freyberg, Peter Friedl, Dirk Kaiser
  • Method for Treating Vascular Disorders
    Publication number: 20090162381
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Application
    Filed: February 20, 2009
    Publication date: June 25, 2009
    Applicant: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Method for Manufacturing Specific Binding Molecules Against Selected Target Molecules, Kit, and Binding Molecules
    Publication number: 20080003563
    Abstract: A method for the isolation of specific molecules which bind highly selectively to chosen target molecules. In particular, due to displacement with a specific competitor, binding molecules are selected which preferably bind to previously known epitopes.
    Type: Application
    Filed: April 29, 2005
    Publication date: January 3, 2008
    Inventors: Gerd Klock, Dirk Kaiser, Mark Freyberg
  • Anti-apoptotically active apatamers
    Publication number: 20070117768
    Abstract: The invention relates to anti-apoptotically active apatamers. The invention describes possible therapeutic and diagnostic applications for, among other things, treating arteriosclerosis, promoting the healing of wounds, treating AIDS, cancer, Alzheimer's disease, systemic lupus erythematosus as well a rheumatoid arthritis and other chronic inflammatory diseases.
    Type: Application
    Filed: December 10, 2004
    Publication date: May 24, 2007
    Applicant: CYTOTOOLS GMBH
    Inventors: Gerd Klock, Mark Freyberg, Dirk Kaiser
  • Method for identifying active anti-apoptosis compounds
    Publication number: 20060172921
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Application
    Filed: January 6, 2006
    Publication date: August 3, 2006
    Applicant: CYTOTOOLS GMBH
    Inventors: Mark Freyberg, Peter Friedl, Dirk Kaiser
  • Method for identifying active anti apoptosis compounds
    Patent number: 7008773
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both IAP and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: March 7, 2006
    Assignee: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Apoptotically active peptides
    Publication number: 20050222020
    Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
    Type: Application
    Filed: December 18, 2002
    Publication date: October 6, 2005
    Inventors: Mark Freyberg, Peter Friedl, Dirk Kaiser
  • Agents, which inhibit apoptosis in cells that are involved in wound healing
    Publication number: 20040101526
    Abstract: The invention relates to the use of substances as a fundamental constituent in wound healing agents. The invention is characterised in that said substances hond to either IAP and/or integrin &agr;v&bgr;3 and/or thrombuspondin-1 in such a way that the bond between thrumbospondin-1 and IAP and/or integrin &agr;v&bgr;3 is inhibited.
    Type: Application
    Filed: August 25, 2003
    Publication date: May 27, 2004
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser