Patents by Inventor Mark A. Gray

Mark A. Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12023637
    Abstract: A droplet generating system includes a reservoir configured to receive an organic fluid and an aqueous fluid, a barrier separating the reservoir into a first reservoir portion and a second reservoir portion, a tube, and an indexer. The barrier is capable of preventing the aqueous fluid from entering the second reservoir portion from the first reservoir portion. The tube is disposed near the barrier, and the tube has a microfluidic channel. The indexer guides the aqueous fluid and the organic fluid into the microfluidic channel so as to form droplets of the aqueous fluid.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: July 2, 2024
    Inventor: Mark A. Gray
  • Publication number: 20240207844
    Abstract: Engineered nanoscale multicomponent particles are introduced and are called “quants.” Methods and apparatuses for producing such multicomponent nanoparticles are provided. A single quant can be manufactured to contain a variety of different internal component molecules. Likewise, a plurality of such quants may be manufactured wherein the plurality of quants are suspended in an aqueous solution. Typically, quants are produced in quantity and concentration adequate to support human scale therapeutics. In some embodiments, millions or billions of quants are suspended in a volume of aqueous solution for delivery to a patient. When manufactured to the same specification, the plurality of quants are uniform in size, uniform in chemical composition, and therefore uniform in functionality. Functional uniformity is an important aspect of quants, manifested in design and production.
    Type: Application
    Filed: July 25, 2023
    Publication date: June 27, 2024
    Inventor: Mark A. Gray
  • Patent number: 11707737
    Abstract: Engineered nanoscale multicomponent particles are introduced and are called “quants.” Methods and apparatuses for producing such multicomponent nanoparticles are provided. A single quant can be manufactured to contain a variety of different internal component molecules. Likewise, a plurality of such quants may be manufactured wherein the plurality of quants are suspended in an aqueous solution. Typically, quants are produced in quantity and concentration adequate to support human scale therapeutics. In some embodiments, millions or billions of quants are suspended in a volume of aqueous solution for delivery to a patient. When manufactured to the same specification, the plurality of quants are uniform in size, uniform in chemical composition, and therefore uniform in functionality. Functional uniformity is an essential aspect of quants, manifested in design and production.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: July 25, 2023
    Inventor: Mark A. Gray
  • Publication number: 20210291129
    Abstract: A droplet generating system includes a reservoir configured to receive an organic fluid and an aqueous fluid, a barrier separating the reservoir into a first reservoir portion and a second reservoir portion, a tube, and an indexer. The barrier is capable of preventing the aqueous fluid from entering the second reservoir portion from the first reservoir portion. The tube is disposed near the barrier, and the tube has a microfluidic channel. The indexer guides the aqueous fluid and the organic fluid into the microfluidic channel so as to form droplets of the aqueous fluid.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 23, 2021
    Inventor: Mark A. Gray
  • Patent number: 11118218
    Abstract: An article for forming emulsion droplets includes a body having an inlet port, an outlet, and a reservoir configured to receive both an aqueous phase and an organic phase through the inlet port. By applying a force to the contents of the reservoir, an aqueous phase stream and a separate organic phase stream from the reservoir are generated and later combined to form emulsion droplets which are dispensed through the outlet, typically into a receptacle for analysis or further processing.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: September 14, 2021
    Assignee: Cypho, Inc.
    Inventor: Mark A. Gray
  • Publication number: 20200254453
    Abstract: Engineered nanoscale multicomponent particles are introduced and are called “quants.” Methods and apparatuses for producing such multicomponent nanoparticles are provided. A single quant can be manufactured to contain a variety of different internal component molecules. Likewise, a plurality of such quants may be manufactured wherein the plurality of quants are suspended in an aqueous solution. Typically, quants are produced in quantity and concentration adequate to support human scale therapeutics. In some embodiments, millions or billions of quants are suspended in a volume of aqueous solution for delivery to a patient. When manufactured to the same specification, the plurality of quants are uniform in size, uniform in chemical composition, and therefore uniform in functionality. Functional uniformity is an essential aspect of quants, manifested in design and production.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Inventor: Mark A. Gray
  • Patent number: 10397645
    Abstract: Apparatuses, methods and storage medium associated with real time closed captioning or highlighting are disclosed herein. In embodiments, an apparatus may include an audio interceptor to intercept an audio portion of an audio/video output stream of a multi-media application; a speech recognizer coupled to the audio interceptor to, in real time, process the audio portion of the audio/video stream, recognize speech within the audio portion, and automatically generate text corresponding to recognized speech, or keywords within the recognized speech; and a controller coupled to the audio interceptor and the speech recognizer, to control operations of the audio interceptor and the speech recognizer. The automatically generated text or keywords may be outputted as closed captions or highlights to complement video content of the audio/video stream. Other embodiments may be disclosed or claimed.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: August 27, 2019
    Assignee: Intel Corporation
    Inventors: Karthik Veeramani, Rajneesh Chowdhury, Mark A. Gray
  • Publication number: 20180277142
    Abstract: Apparatuses, methods and storage medium associated with real time closed captioning or highlighting are disclosed herein. In embodiments, an apparatus may include an audio interceptor to intercept an audio portion of an audio/video output stream of a multi-media application; a speech recognizer coupled to the audio interceptor to, in real time, process the audio portion of the audio/video stream, recognize speech within the audio portion, and automatically generate text corresponding to recognized speech, or keywords within the recognized speech; and a controller coupled to the audio interceptor and the speech recognizer, to control operations of the audio interceptor and the speech recognizer. The automatically generated text or keywords may be outputted as closed captions or highlights to complement video content of the audio/video stream. Other embodiments may be disclosed or claimed.
    Type: Application
    Filed: March 23, 2017
    Publication date: September 27, 2018
    Inventors: KARTHIK VEERAMANI, RAJNEESH CHOWDHURY, MARK A. GRAY
  • Publication number: 20160167053
    Abstract: An article for forming emulsion droplets includes a body having an inlet port, an outlet, and a reservoir configured to receive both an aqueous phase and an organic phase through the inlet port. By applying a force to the contents of the reservoir, an aqueous phase stream and a separate organic phase stream from the reservoir are generated and later combined to form emulsion droplets which are dispensed through the outlet, typically into a receptacle for analysis or further processing.
    Type: Application
    Filed: December 9, 2013
    Publication date: June 16, 2016
    Applicant: CYPHO, INC.
    Inventor: Mark A. GRAY
  • Publication number: 20140193857
    Abstract: A centrifuge tube droplet generator includes a centrifugally generated droplet system which accommodates a sample volume of below 20 microliters and below. The system has virtually no dead volume, is simple and inexpensive and can therefore be realized in a disposable unit. The system can be tailored to fit the format of standard desktop centrifuges which are ubiquitous in biological laboratories.
    Type: Application
    Filed: September 11, 2013
    Publication date: July 10, 2014
    Applicant: Cypho, Inc.
    Inventor: Mark A. Gray
  • Patent number: 5426677
    Abstract: A pressurizer vessel of a nuclear power plant contains a liquid and steam both of which function to maintain pressure in a reactor coolant system. A heater support assembly is disposed in an interior portion of the pressurizer vessel and receive a plurality of heaters which are matingly fitted with the heater support assembly for heating the liquid. A temperature detector is operatively connected to the heater support assembly in a structural arrangement which allows for measuring the temperature of the liquid at a plurality of preselected elevations. The temperature detector further includes temperature measuring means for measuring a plurality of temperature readings of the liquid at preselected elevations of the liquid.
    Type: Grant
    Filed: January 3, 1994
    Date of Patent: June 20, 1995
    Assignee: Westinghouse Electric Corporation
    Inventors: Elwyn L. Cranford, III, Mark A. Gray