Patents by Inventor Mark A. Hardy

Mark A. Hardy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7560555
    Abstract: A process for the preparation of a compound of formula R1—Y1—P(NR2R3)2 is provided. The process comprises reacting a compound of formula PX3 with a compound of formula HNR2R3 to form a compound of formula X—P(NR2R3)2; and reacting the compound of formula X—P(NR2R3)2 with a compound of formula R1—Y1—H in the presence of a hydrocarbon solvent to form the compound of formula R1—Y1—P(NR2R3)2. R1 represents a phosphorus protecting group; R2 and R3 each independently represent an alkyl, prefer-ably a C1-6alkyl, group, or R2 and R3 are joined, together with the N to which they are attached, to form a 5-7 membered ring; Y1 represents O or S, preferably O; and X represents a halogen, preferably Cl. The preferred solvent is toluene.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: July 14, 2009
    Assignee: Avecia Biotechnology Inc.
    Inventors: Jonathan Mark Hardy, Stephen Edward Dinizo
  • Publication number: 20070198586
    Abstract: An interactive geospatial data provisioning application presents a graphical user interface operable to present a map of geographic regions and corresponding geospatial data sets. The user selects the area of interest from the mapped regions corresponding to the available geospatial data sets. The application identifies geospatial data sets within the area of interest. By analyzing the attributes available in the identified geospatial data sets, the geospatial data application determines the operations applicable to the data sets. A set of transformation rules computes the operations available for a particular selection of geospatial data sets. A custom plugin generator allows a user to define and insert geospatial operations into the provisioning sequence. The application presents the available predefined and user defined operations, and the user select the geospatial data operations to apply from among the available operations.
    Type: Application
    Filed: February 22, 2006
    Publication date: August 23, 2007
    Inventors: Mark Hardy, Philip Barker, Mark Koch
  • Publication number: 20070168370
    Abstract: An interactive geospatial data provisioning application presents a graphical user interface operable to present a map of geographic regions and corresponding geospatial data sets available. The user selects the area of interest by panning and zooming over the mapped regions corresponding to the available geospatial data sets. The application identifies geospatial data sets within the area of interest. By analyzing the attributes available in the identified geospatial data sets, the geospatial data application determines the operations applicable to the data sets. A set of transformation rules computes the operations available for a particular selection of geospatial data sets. The application presents the available operations, and the user select the geospatial data operations to apply from among the available operations.
    Type: Application
    Filed: November 16, 2004
    Publication date: July 19, 2007
    Inventor: Mark Hardy
  • Patent number: 6618863
    Abstract: An item of clothing the width of a component part of which can be adjusted by the user, the clothing item having a line or cord (1) at least partly encircling the relevant part, which cord can be pulled by the wearer to adjust the width or tightness of the part by means of gathering of the material of the part around the line or cord. For the part of the circumference of the relevant part the cord is concealed under the material but emerges at a desired point and them passes again to the inside of the item of clothing so as to form a cord pull section (6) on the inside of the clothing. The clothing item includes means (5) for holding the component part in its tightened or gathered condition about the cord, the cord pull section (6) being used by the wearer for adjustment of the width of the relevant part.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: September 16, 2003
    Inventor: Bernard Mark Hardy Blechman
  • Publication number: 20020029407
    Abstract: The present application describes an item of clothing the width of a component part of which can be adjusted by the user, the clothing item having a line or cord (1) at least partly encircling the relevant part, which cord can be pulled by the wearer to adjust the width or tightness of the part by means of gathering of the material of the part around the line or cord. For the part of the circumference of the relevant part the cord is concealed under the material but emerges at a desired point and then passes again to the inside of the item of clothing so as to form a cord pull section (6) on the inside of the clothing. The clothing item includes means (5) for holding the component part in its tightened or gathered condition about the cord, the cord pull section (6) being used by the wearer for adjustment of the width of the relevant part.
    Type: Application
    Filed: January 18, 2001
    Publication date: March 14, 2002
    Inventor: Bernard Mark Hardy Blechman
  • Patent number: 4946438
    Abstract: A patient's acceptance of transplanted organs and tissues may be enhanced by treating donor specific blood with a suitable dose of ultraviolet radiation for an appropriate period of time, transfusing the irradiated blood into the patient during a suitable pretransplantation time period and then transplanting the organ or tissue into the subject. Acceptance of transplanted organs and tissues can also be enhanced by treating the organs or tissues to be transplanted with a suitable dose of ultraviolet radiation for an appropriate period of time and then transplanting the organ or tissue. Suitably irradiated donor specific blood, organs and tissues are preferred for use in transplantation.
    Type: Grant
    Filed: June 12, 1989
    Date of Patent: August 7, 1990
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Keith Reemtsma, Mark A. Hardy, Henry T. Lau
  • Patent number: 4861704
    Abstract: A patient's acceptance of a transplanted organ or tissue from a donor may be enhanced by irradiating donor-specific blood with ultraviolet-B radiation at a dosage of less than 1000 J/M.sup.2 so as to render the blood capable of inducing donor-specific immunological unresponsiveness in the patient, transfusing the irradiated, donor-specific blood into the patient prior to transplanting the organ or tissue into the patient to enhance subsequent acceptance of the organ or tissue by the patient, and thereafter transplanting the organ or tissue into the subject.A patient's acceptance of transplanted organs and tissues can also be enhanced by removing the organ or tissue from the donor and irradiating the organ or tissue to be transplanted with ultraviolet-B radiation at a dosage of less than 1000 J/m.sup.2 so as to enhance acceptance of the transplanted organ or tissue and then transplanting the irradiated organ or tissue into patient.
    Type: Grant
    Filed: October 8, 1986
    Date of Patent: August 29, 1989
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Keith Reemtsma, Mark A. Hardy, Henry T. Lau
  • Patent number: D446383
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: August 14, 2001
    Inventor: Bernard Mark Hardy Blechman